CAJ | 학술논문

目的探讨周围组织与乳腺病灶的应变比值( strain ratio,SR)鉴别常规超声分级为BI-RADS 4级乳腺病灶良恶性的应用价值.方法 64例(良性34例,恶性30例)常规超声诊断为BI-RADS 4级乳腺病灶,通过超声弹性成像获得周围组织与乳腺病灶的SR,以穿刺活检或手术病理结果为标准,分析良、恶性病灶SR之间的差异,应用ROC曲线评价SR鉴别乳腺可疑恶性病变的价值.结果 34例良性乳腺病灶及30例恶性乳腺病灶的SR值分别为2.85±1.30及5.03±2.50,两者间差异有统计学意义(t=-4.29,P=0.000).应用SR鉴别常规超声分级为BI-RADS 4级乳腺病灶的良恶性,ROC曲线下面积为0.875(P ＜0.0001).当SR诊断阈值取3.26时,鉴别常规超声分级为BI-RADS 4级乳腺病灶良恶性的敏感性为83.33％,特异性为82.35％.结论超声弹性参数SR对常规超声发现的乳腺BI-RADS 4级病灶的鉴别诊断有较好的应用价值.
목적 탐토주위조직여유선병조적응변비치( strain ratio,SR)감별상규초성분급위BI-RADS 4급유선병조량악성적응용개치.방법 64례(량성34례,악성30례)상규초성진단위BI-RADS 4급유선병조,통과초성탄성성상획득주위조직여유선병조적SR,이천자활검혹수술병리결과위표준,분석량、악성병조SR지간적차이,응용ROC곡선평개SR감별유선가의악성병변적개치.결과 34례량성유선병조급30례악성유선병조적SR치분별위2.85±1.30급5.03±2.50,량자간차이유통계학의의(t=-4.29,P=0.000).응용SR감별상규초성분급위BI-RADS 4급유선병조적량악성,ROC곡선하면적위0.875(P ＜0.0001).당SR진단역치취3.26시,감별상규초성분급위BI-RADS 4급유선병조량악성적민감성위83.33％,특이성위82.35％.결론 초성탄성삼수SR대상규초성발현적유선BI-RADS 4급병조적감별진단유교호적응용개치.
Objective To assessment the value of strain ratio(SR) in differentiating benign and malignant breast lesions of BI-RADS Ⅳ diagnosed by conventional ultrasound.Methods Elastosonography was performed on 64 patients with breast lesions of BI-RADS Ⅳ diagnosed by conventional ultrasound.SR (strainnormal neighboring tissues /strainbreast lesion) was calculated by the software equipped with the ultrasonic machine.Pathology of the lesions after biopsy or operation was considered as standard,SRs of benign and malignant breast lesions were compared with independent-samples t test.The diagnostic value of SR was evaluated by receiver operating characteristic (ROC) curve analysis.Results SRs of 34 benign breast lesions and 30 malignant breast lesions were 2.85 ± 1.30 and 5.03 ± 2.50 respectively,there was significant difference between them( t =- 4.29,P =0.000).Area under the curve of diagnosing benign and malignant of breast lesions was 0.875 for SR( P ＜0.0001).If the cut-off point of SR was 3.26,the sensitivity in differentiating breast lesions was 83.33％,while the specificity was 82.35％.Conclusions SR is a helpful elasticity parameter for differentiating benign and malignant breast lesions of BI-RADS Ⅳ diagnosed by conventional ultrasound.