中华创伤杂志
中華創傷雜誌
중화창상잡지
Chinese Journal of Traumatology
2012年
4期
353-356
,共4页
陈黎虬%邓敦%颜海波%王朝晖%张文斌%张维康%竺利民%陈笑宇%颜佩华%李登斐%黄华芳
陳黎虬%鄧敦%顏海波%王朝暉%張文斌%張維康%竺利民%陳笑宇%顏珮華%李登斐%黃華芳
진려규%산돈%안해파%왕조휘%장문빈%장유강%축이민%진소우%안패화%리등비%황화방
麻醉和镇痛%外科手术%帕瑞昔布钠
痳醉和鎮痛%外科手術%帕瑞昔佈鈉
마취화진통%외과수술%파서석포납
Anesthesia and analgesia%Surgical procedures,operative%Parecoxib sodium
目的 探讨帕瑞昔布钠联合硬脊膜外自控镇痛(patient controlled epidural analgesia,PCEA)对骨科蛛网膜下腔阻滞麻醉患者术后镇痛效果. 方法 200例骨科蛛网膜下腔阻滞麻醉手术患者按随机数字表法分为帕瑞昔布钠治疗组(P组)、曲马多对照组(C组),每组各100例.P组于手术结束时静脉注射帕瑞昔布钠40mg+ PCEA,C组使用曲马多注射液0.5 g+PCEA.两组均于手术结束离室时启用PCEA镇痛.对两组术后6,12,24,48,72 h进行视觉模拟疼痛评分(VAS),记录镇痛泵按压次数、有效次数及不良反应和满意度. 结果 术后6,12,24,48,72 hVAS评分P组低于C组(P＜0.05)；12,24h镇痛泵按压次数、有效次数及不良反应P组均低于C组,满意度P组高于C组(P＜0.05). 结论 帕瑞昔布钠联合PCEA对骨科蛛网膜下腔阻滞麻醉患者术后镇痛效果更佳,不良反应发生率较低.
目的 探討帕瑞昔佈鈉聯閤硬脊膜外自控鎮痛(patient controlled epidural analgesia,PCEA)對骨科蛛網膜下腔阻滯痳醉患者術後鎮痛效果. 方法 200例骨科蛛網膜下腔阻滯痳醉手術患者按隨機數字錶法分為帕瑞昔佈鈉治療組(P組)、麯馬多對照組(C組),每組各100例.P組于手術結束時靜脈註射帕瑞昔佈鈉40mg+ PCEA,C組使用麯馬多註射液0.5 g+PCEA.兩組均于手術結束離室時啟用PCEA鎮痛.對兩組術後6,12,24,48,72 h進行視覺模擬疼痛評分(VAS),記錄鎮痛泵按壓次數、有效次數及不良反應和滿意度. 結果 術後6,12,24,48,72 hVAS評分P組低于C組(P＜0.05)；12,24h鎮痛泵按壓次數、有效次數及不良反應P組均低于C組,滿意度P組高于C組(P＜0.05). 結論 帕瑞昔佈鈉聯閤PCEA對骨科蛛網膜下腔阻滯痳醉患者術後鎮痛效果更佳,不良反應髮生率較低.
목적 탐토파서석포납연합경척막외자공진통(patient controlled epidural analgesia,PCEA)대골과주망막하강조체마취환자술후진통효과. 방법 200례골과주망막하강조체마취수술환자안수궤수자표법분위파서석포납치료조(P조)、곡마다대조조(C조),매조각100례.P조우수술결속시정맥주사파서석포납40mg+ PCEA,C조사용곡마다주사액0.5 g+PCEA.량조균우수술결속리실시계용PCEA진통.대량조술후6,12,24,48,72 h진행시각모의동통평분(VAS),기록진통빙안압차수、유효차수급불량반응화만의도. 결과 술후6,12,24,48,72 hVAS평분P조저우C조(P＜0.05)；12,24h진통빙안압차수、유효차수급불량반응P조균저우C조,만의도P조고우C조(P＜0.05). 결론 파서석포납연합PCEA대골과주망막하강조체마취환자술후진통효과경가,불량반응발생솔교저.
Objective To investigate the analgesic effects of parecoxib sodium combined with patient controlled epidural analgesia (PCEA) after orthopedic subarachnoid block anesthesia surgery.Methods Two hundred patients undergone orthopedic subarachnoid block anesthesia surgery were randomly and equally divided into two groups:Group P (treated intravenously with 40 mg parecoxib sodium combined with PCEA at the end of operation) and Group C ( treated intravenously with 0.5 g tramadol combined with PCEA at the end of operation).The visual analog scale (VAS) was performed at 6,12,24,48 and 72 hours postoperatively in two groups.Meanwhile,the press frequency of analgesic pump,effective frequency,side effects and satisfaction degree were recorded. Results The VAS sore of Group P was lower than that of Group C at 6,12,24,48 and 72 hours postoperatively ( P ＜ 0.05 ).Group P showed a less number in aspects of the press frequency of analgesic pump,effective frequency,and side effects at 12 and 24 hours,but a higher satisfactory degree,compared with Group C (P ＜0.05). Conclusion Combined use of parecoxib sodium and PCEA can exert a better analgesic effect and have a low incidence rate of side effects following orthopedic subarachnoid block anesthesia.
