CAJ | 학술논문

目的研究高膳食纤维肠内营养对危重症患者营养状况及耐受性的影响.方法将78例危重症患者随机分成标准肠内营养乳剂组(对照组)和高膳食纤维肠内营养乳剂组(研究组),每组39例.观察肠内营养支持10d后,患者营养状况、胃肠道并发症及耐受性.结果对照组与研究组各项指标在治疗前均无明显差异(P均＞0.05).与治疗前比较,治疗10d后两组患者的体质量指数、皮褶厚度、上臂围等均有所改善,但差异均无统计学意义(P均＞0.05)；治疗后两组血糖、血清总蛋白、白蛋白、血红蛋白均显著增加(P均＜0.05),但治疗后研究组血糖增高明显小于对照组,血清胆固醇及甘油三酯水平均明显高于对照组(P均＜0.05).研究组肠内营养期间胃肠道并发症、过渡到全量肠内营养时间均显著小于对照组(P均＜0.05).结论高膳食纤维肠内营养支持治疗,不仅有助于改善危重症患者营养状况,还增加了患者对肠内营养的耐受性.
목적 연구고선식섬유장내영양대위중증환자영양상황급내수성적영향.방법 장78례위중증환자수궤분성표준장내영양유제조(대조조)화고선식섬유장내영양유제조(연구조),매조39례.관찰장내영양지지10d후,환자영양상황、위장도병발증급내수성.결과 대조조여연구조각항지표재치료전균무명현차이(P균＞0.05).여치료전비교,치료10d후량조환자적체질량지수、피습후도、상비위등균유소개선,단차이균무통계학의의(P균＞0.05)；치료후량조혈당、혈청총단백、백단백、혈홍단백균현저증가(P균＜0.05),단치료후연구조혈당증고명현소우대조조,혈청담고순급감유삼지수평균명현고우대조조(P균＜0.05).연구조장내영양기간위장도병발증、과도도전량장내영양시간균현저소우대조조(P균＜0.05).결론 고선식섬유장내영양지지치료,불부유조우개선위중증환자영양상황,환증가료환자대장내영양적내수성.
Objective To evaluate the effect of high dietary fiber enteral nutrition (EN)on nutritional status and tolerance in critically ill patients.Methods Seventy-eight cases of critically ill patients were randomly divided into control group (complete EN emulsion,39cases) and study group (EN emulsion with high dietary fiber,39 cases).The nutrition status,gastrointestinal complications and EN tolerance were measured before and after 10 d EN treatment.Results There was no significant difference in all the parameters between the two groups before EN treatment (all P ＞ 0.05).However,10 d after EN,the status of body mass index,skinfold thickness,and upper-arm circumference were improved but not statistically different in the two groups (all P ＞ 0.05).The levels of blood glucose,serum total protein,albumin,and hemoglobin were narkedly increased after EN treatment in both groups (all P＜ 0.05).After EN treatment,compared with the control group,the increase of blood glucose was markedly weakened and the serum total cholesterol,triglyceride were significantly enhanced in the study group (all P ＜ 0.05).The gastrointestinal complications and the transition time of total EN were significantly decreased in the study group as compared with the control group (all P ＜ 0.05).Conclusion EN treatment with the high dietary fiber could help to improve nutritional status and the EN-related tolerance in critically ill patients.