CAJ | 학술논문

目的探讨紫杉醇联合顺铂同步放化疗治疗中晚期宫颈癌临床疗效.方法晚期宫颈癌患者随机分为对照组以及观察组,其中观察组患者采用紫杉醇联合顺铂同步放化疗治疗,对照组患者采用氟尿嘧啶、博来霉素以及顺铂进行治疗.结果观察组患者临床有效率为84.5％,高于对照组的65.0％(P＜0.05)；观察组骨髓抑制、消化道反应出现机会以及严重程度均高于对照组(P＜0.05)；两组临床毒副作用出现例次差异无统计学意义(P＞0.05).结论对中晚期宫颈癌患者采用紫杉醇联合顺铂同步放化疗进行治疗,可有效提高患者治疗效果,提高患者生存时间.
목적 탐토자삼순연합순박동보방화료치료중만기궁경암림상료효.방법 만기궁경암환자수궤분위대조조이급관찰조,기중관찰조환자채용자삼순연합순박동보방화료치료,대조조환자채용불뇨밀정、박래매소이급순박진행치료.결과 관찰조환자림상유효솔위84.5％,고우대조조적65.0％(P＜0.05)；관찰조골수억제、소화도반응출현궤회이급엄중정도균고우대조조(P＜0.05)；량조림상독부작용출현례차차이무통계학의의(P＞0.05).결론 대중만기궁경암환자채용자삼순연합순박동보방화료진행치료,가유효제고환자치료효과,제고환자생존시간.
Objective To investigate the clinical efficacy of simultaneous release of paclitaxel and cisplatin chemotherapy in treatment advanced cervical cancer.Methods 90 patients with advanced cervical cancer were randomly divided into control and experimental group,the experimental group was treated with paclitaxel and cisplatin concurrent radiotherapy and chemotherapy treatment,the control group was treated with 5-Fu,bleomycin and cisplatin for treatment.Results The clinical effective rate was 84.5％,which was higher than that of the control group (65.0％) ( P ＜ 0.05 ) ; experimental group of patients whose bone marrow suppression and gastrointestinal disorders as well as opportunities arise severity were higher( P ＜ 0.05 ) ; two groups of patients the clinical side effects appear no significant differences in case-times( P ＞ 0.05 ).Conclusion The use of paclitaxel in advanced cervical cancer and cisplatin in patients with concurrent radiotherapy and chemotherapy treatment,which could effectively improve patient outcomes,improve patient survival.