中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2011年
3期
222-225
,共4页
迟子锋%韩春%刘丹%曹彦坤%李润霄
遲子鋒%韓春%劉丹%曹彥坤%李潤霄
지자봉%한춘%류단%조언곤%리윤소
前列腺肿瘤/调强放射疗法%蒙特卡罗%治疗计划系统
前列腺腫瘤/調彊放射療法%矇特卡囉%治療計劃繫統
전렬선종류/조강방사요법%몽특잡라%치료계화계통
Prostate neoplasms/intensity modulated radiotherapy%Monte Carlo%Treatment planning system
目的 使用蒙特卡罗方法 独立计算、评估及比较4种商用治疗计划系统设计的前列腺癌调强放疗(IMRT)计划质量,为临床选择治疗计划系统提供参考和依据.方法 分别使用Corvus、Xio、Pinnacle和Eclipse治疗计划系统设计11例前列腺癌IMRT计划.所有子野和机器跳数(MU)均移植到蒙特卡罗系统重新计算并比较,以临床接受标准评估剂量体积直方图和等剂量曲线分布[如99%CTV或PrV接受的最小剂量(Dmin),1%CTV或PTV接受的最大剂量(Dmax),接受110%、105%、95%处方剂量的CTV或PTV体积(V110%.、V105%、V95%),接受>65、>加Gy照射的直肠和膀胱体积(V65、V40),接受>50 Gy照射的股骨头体积(V50)].结果 蒙特卡罗和4种计划计算结果 剂量分布一致性都在3%/3 mm以内.与Corvus计划相比,Xio、Pinnacle、Eclipse计划结果 显示较低的靶区剂量差异,直肠和膀胱V65、V40也较低.和其他治疗计划结果 相比,Xio计划的PTV最小剂茸约低2 Gy,Corvus计划的股骨头V50较低(0.03%和0.58%).Corvus计划需子野数和MU数最多(187.8和1264.7),Pinnacle计划需要的最少(82.4和703.6).结论 独立的蒙特卡罗系统能完成剂量重建和计划评估,并提供了一个公平的比较和评价治疗计划的平台,有助于临床选择更适合的治疗计划系统.用瓦里安23EX加速器对前列腺癌IMRT计划的设计结果 显示更倾向于用Pinnacle、Eclipse治疗计划系统.
目的 使用矇特卡囉方法 獨立計算、評估及比較4種商用治療計劃繫統設計的前列腺癌調彊放療(IMRT)計劃質量,為臨床選擇治療計劃繫統提供參攷和依據.方法 分彆使用Corvus、Xio、Pinnacle和Eclipse治療計劃繫統設計11例前列腺癌IMRT計劃.所有子野和機器跳數(MU)均移植到矇特卡囉繫統重新計算併比較,以臨床接受標準評估劑量體積直方圖和等劑量麯線分佈[如99%CTV或PrV接受的最小劑量(Dmin),1%CTV或PTV接受的最大劑量(Dmax),接受110%、105%、95%處方劑量的CTV或PTV體積(V110%.、V105%、V95%),接受>65、>加Gy照射的直腸和膀胱體積(V65、V40),接受>50 Gy照射的股骨頭體積(V50)].結果 矇特卡囉和4種計劃計算結果 劑量分佈一緻性都在3%/3 mm以內.與Corvus計劃相比,Xio、Pinnacle、Eclipse計劃結果 顯示較低的靶區劑量差異,直腸和膀胱V65、V40也較低.和其他治療計劃結果 相比,Xio計劃的PTV最小劑茸約低2 Gy,Corvus計劃的股骨頭V50較低(0.03%和0.58%).Corvus計劃需子野數和MU數最多(187.8和1264.7),Pinnacle計劃需要的最少(82.4和703.6).結論 獨立的矇特卡囉繫統能完成劑量重建和計劃評估,併提供瞭一箇公平的比較和評價治療計劃的平檯,有助于臨床選擇更適閤的治療計劃繫統.用瓦裏安23EX加速器對前列腺癌IMRT計劃的設計結果 顯示更傾嚮于用Pinnacle、Eclipse治療計劃繫統.
목적 사용몽특잡라방법 독립계산、평고급비교4충상용치료계화계통설계적전렬선암조강방료(IMRT)계화질량,위림상선택치료계화계통제공삼고화의거.방법 분별사용Corvus、Xio、Pinnacle화Eclipse치료계화계통설계11례전렬선암IMRT계화.소유자야화궤기도수(MU)균이식도몽특잡라계통중신계산병비교,이림상접수표준평고제량체적직방도화등제량곡선분포[여99%CTV혹PrV접수적최소제량(Dmin),1%CTV혹PTV접수적최대제량(Dmax),접수110%、105%、95%처방제량적CTV혹PTV체적(V110%.、V105%、V95%),접수>65、>가Gy조사적직장화방광체적(V65、V40),접수>50 Gy조사적고골두체적(V50)].결과 몽특잡라화4충계화계산결과 제량분포일치성도재3%/3 mm이내.여Corvus계화상비,Xio、Pinnacle、Eclipse계화결과 현시교저적파구제량차이,직장화방광V65、V40야교저.화기타치료계화결과 상비,Xio계화적PTV최소제용약저2 Gy,Corvus계화적고골두V50교저(0.03%화0.58%).Corvus계화수자야수화MU수최다(187.8화1264.7),Pinnacle계화수요적최소(82.4화703.6).결론 독립적몽특잡라계통능완성제량중건화계화평고,병제공료일개공평적비교화평개치료계화적평태,유조우림상선택경괄합적치료계화계통.용와리안23EX가속기대전렬선암IMRT계화적설계결과 현시경경향우용Pinnacle、Eclipse치료계화계통.
Objective With the Monte Carlo method to recaleulate the IMRT dose distributions from four TPS to provide a platform for independent comparison and evaluation of the plan quality.These results wiU help make a clinical decision as which TPS will be used for prostate IMRT planning.Methods Eleven prostate cancer cases were planned with the Corvus,Xio,Pinnacle and Eclipse TPS.The plans were recalculated bv Monte Cado using leaf sequences and MUs for individual plans.Dose-volume-histograms and isodose distributions were compared.Other quantities such as Dmin(the minimum dose received by 99% of CTV/PTV),Dmax(the maximum dose received by 1%of CTV/PTV),V110%,V105%,V95%(the volume of CTV/PTV receiving 110%,105%.95% of the prescription dose),the volume of rectum and bladder receiving>65 Gy and>40 Gy,and the volume of femur receiving>50 Gy were evaluated.Total segments and MUs were also compared.Results The Monte Carlo results agreed with the dose distributions from the TPS to within 3%/3 mm.The Xio,Pinnacle and Eclipse plans show less target dose heterogeneity and lower V65 and V40 for the rectum and bladder compared to the Corvus plans.The PTV Dmin is about 2 Gy lower for Xio plans than others while the Corvus plans have slightly lower female head V50(0.03%and 0.58%)than others.The Corvus plans require significantly most segments(187.8)and MUs(1264.7)to deliver and the Pinnacle plans require fewest segments(82.4)and MUs(703.6).Conclusions We have tested an independent Monte Carlo dose catculation system for dose reconstruction and plan evaluation.This system provides a platform for the fair comparison and evaluation of treatment plans to facilitate clinical decision making in selecting a TPS and beam delivery system for particular treatment sites.
