CAJ | 학술논문

应用聚合酶链反应技术和基因测序技术检测中国汉族男性群体葡萄糖转运蛋白(GLUT)9基因rs13137343位点基因多态性与原发性高尿酸血症的遗传易感性关系.结果显示,原发性高尿酸血症组GLUT9基因rs13137343位点基因型分布和正常对照组比较差异有统计学意义(x2=7.024,P=0.030).
응용취합매련반응기술화기인측서기술검측중국한족남성군체포도당전운단백(GLUT)9기인rs13137343위점기인다태성여원발성고뇨산혈증적유전역감성관계.결과현시,원발성고뇨산혈증조GLUT9기인rs13137343위점기인형분포화정상대조조비교차이유통계학의의(x2=7.024,P=0.030).
A possible association between the polymorphism of glucose transporter 9 (GLUT9) rs1 3137343 and hyperuricemia was investigated in Chinese male population and the calculated genotype frequencies and allelic frequencies by PCR method and direct sequencing were reported.Data showed that there was statistical difference in GLUT9 rs13137343 genotype frequencies between hyperuricemia cases and controls(x2 =7.024,P =0.030).