CAJ | 학술논문

H~+/K~+-ATP酶抑制剂对于胃溃疡治疗具有划时代意义,我们对其中四种苯并咪唑药物的红外光谱进行分析,对药物结构与光谱特征相关性作探讨分析,研究表明药物的红外谱图指纹特征吸收提供了有关分子结构的有用信息,为药物分子的结构确定和新药物开发提供重要的依据.
H~+/K~+-ATP매억제제대우위궤양치료구유화시대의의,아문대기중사충분병미서약물적홍외광보진행분석,대약물결구여광보특정상관성작탐토분석,연구표명약물적홍외보도지문특정흡수제공료유관분자결구적유용신식,위약물분자적결구학정화신약물개발제공중요적의거.
H~+/K~+-ATPase inhibitors is an epoch-making druges on the treatment of gastric ulcer.Four kinds of inhibitors Pyridylsulfinylbenzimidazole druges was analysed with infrared spectroscopy and characterization relations of their structures and the vibration frequencies of their spectra was studied.The results show that the IR vibration frequencies provided the massages on the difference of structures of druges,our research is useful and valuable for pharmaceutical identification and the development of new chemical compound.