CAJ | 학술논문

目的探讨狼疮性肾炎(LN)的病理类型与临床及实验室检查的关系.方法对34例狼疮性肾炎患者进行肾活检及病理分型,分析各病理类型的临床特点、实验室检查特点、临床活动性及肾脏病理活动性.结果病理类型Ⅳ型最多见(占55.9%),Ⅳ型LN肾功能不全及血尿发生率高,肾脏病理活动性明显:Ⅳ型、Ⅴ型、Ⅴ+Ⅳ、Ⅴ+ⅢLN肾病综合征、大量蛋白尿发生率高.肾脏病理活动指数与系统性红斑狼疮的临床活动性及抗dsDNA抗体阳性率无相关性.结论狼疮性肾炎的病理类型与临床表现、实验窒检查有一定联系;但二者之间关系不确定.
목적 탐토랑창성신염(LN)적병리류형여림상급실험실검사적관계.방법 대34례랑창성신염환자진행신활검급병리분형,분석각병리류형적림상특점、실험실검사특점、림상활동성급신장병리활동성.결과 병리류형Ⅳ형최다견(점55.9%),Ⅳ형LN신공능불전급혈뇨발생솔고,신장병리활동성명현:Ⅳ형、Ⅴ형、Ⅴ+Ⅳ、Ⅴ+ⅢLN신병종합정、대량단백뇨발생솔고.신장병리활동지수여계통성홍반랑창적림상활동성급항dsDNA항체양성솔무상관성.결론 랑창성신염적병리류형여림상표현、실험질검사유일정련계;단이자지간관계불학정.
Objectives To evaluate the relation between pathologic type of lupus nephritis(LN)and its clinical findings and the labemtory examination.Methods The renal biopsy was made in 34 cages of lupus nephritis and were classified.To analyse the clinical features and the laboratory examination features and clinical activity and renal pathologic activity of pathologic types.Results Ⅳ type.LN Wag most conlmon(55.9%),in Ⅳ type LN,there Wag hish incidence of hematuria and renal insufficiency,and renal pathologic activity Wag marked;In Ⅳ type、Ⅴtype、Ⅳ+Ⅴtype and Ⅲ+Ⅴtype LN.therewere hishincidencein nephrotic syndromeandsevere proteinuria.There was no relation between acute activity index of renal pathology and SLE clinical activity index.The same result Wag found in renal pathological acute index and anti-dsDNA antibody levels.Conclusions There is relation between LN pathological change and LN clinical manifestation and laboratory examination.but their degrees are different.