中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2010年
4期
286-289
,共4页
角膜磨镶术,激光原位,微型角膜刀%角膜上皮下雾状混浊%屈光回退%泪膜
角膜磨鑲術,激光原位,微型角膜刀%角膜上皮下霧狀混濁%屈光迴退%淚膜
각막마양술,격광원위,미형각막도%각막상피하무상혼탁%굴광회퇴%루막
Keratomileusis,laser in situ,epipolis%Haze%Refractive regression%Tear film
目的 观察机械法准分子激光上皮瓣下角膜磨镶术(Epi-LASIK)后泪膜和眼表的变化,探讨其与haze及屈光回退的关系.方法 低中度近视214眼和高度近视154眼行Epi-LASIK手术,分别于术前和术后行泪膜破裂时间(BUT)、泪液分泌量(Schirmer Ⅰ试验)和角膜荧光素染色检查,并观察术后haze和屈光回退情况,对相关数据进行t检验和相关统计分析.结果 术后1个月87跟(23.6%)出现0.5级或1级haze,术后3个月69眼(18.8%),术后6个月48眼(13.0%).术后6个月37眼(10.1%)出现屈光回退.出现haze和屈光回退的病例均属于高度近视组.低中度近视组和高度近视组术后BUT值均有不同程度减小.术后1、3、6个月,高度近视组的BUT下降程度较低中度近视组明显,差异有统计学意义(t=6.82、7.51、6.73,P均＜0.05).低中度近视组和高度近视组泪液分泌量术后与术前相比差异均无统计学意义,术后两组之间泪液分泌量差异亦无统计学意义.术后1、3、6个月,高度近视组角膜荧光素染色点的数量明显多于低中度近视组(t=5.48、5.23、7.67,P均＜0.05).术后1、3、6个月,高度近视组中haze的发生与BUT下降幅度和角膜荧光素染色点的数量呈正相关(r=0.892、0.881,P均＜0.05).术后6个月,高度近视组屈光回退眼的BUT值下降幅度较无屈光回退眼更明显,差异有统计学意义(t=5.50,P＜0.05);屈光回退眼角膜荧光素染色点的数量明显多于无屈光回退眼(t=5.27,P＜0.05).结论 Epi-LASIK术后泪膜和眼表变化与haze及屈光回退密切相关.
目的 觀察機械法準分子激光上皮瓣下角膜磨鑲術(Epi-LASIK)後淚膜和眼錶的變化,探討其與haze及屈光迴退的關繫.方法 低中度近視214眼和高度近視154眼行Epi-LASIK手術,分彆于術前和術後行淚膜破裂時間(BUT)、淚液分泌量(Schirmer Ⅰ試驗)和角膜熒光素染色檢查,併觀察術後haze和屈光迴退情況,對相關數據進行t檢驗和相關統計分析.結果 術後1箇月87跟(23.6%)齣現0.5級或1級haze,術後3箇月69眼(18.8%),術後6箇月48眼(13.0%).術後6箇月37眼(10.1%)齣現屈光迴退.齣現haze和屈光迴退的病例均屬于高度近視組.低中度近視組和高度近視組術後BUT值均有不同程度減小.術後1、3、6箇月,高度近視組的BUT下降程度較低中度近視組明顯,差異有統計學意義(t=6.82、7.51、6.73,P均＜0.05).低中度近視組和高度近視組淚液分泌量術後與術前相比差異均無統計學意義,術後兩組之間淚液分泌量差異亦無統計學意義.術後1、3、6箇月,高度近視組角膜熒光素染色點的數量明顯多于低中度近視組(t=5.48、5.23、7.67,P均＜0.05).術後1、3、6箇月,高度近視組中haze的髮生與BUT下降幅度和角膜熒光素染色點的數量呈正相關(r=0.892、0.881,P均＜0.05).術後6箇月,高度近視組屈光迴退眼的BUT值下降幅度較無屈光迴退眼更明顯,差異有統計學意義(t=5.50,P＜0.05);屈光迴退眼角膜熒光素染色點的數量明顯多于無屈光迴退眼(t=5.27,P＜0.05).結論 Epi-LASIK術後淚膜和眼錶變化與haze及屈光迴退密切相關.
목적 관찰궤계법준분자격광상피판하각막마양술(Epi-LASIK)후루막화안표적변화,탐토기여haze급굴광회퇴적관계.방법 저중도근시214안화고도근시154안행Epi-LASIK수술,분별우술전화술후행루막파렬시간(BUT)、루액분비량(Schirmer Ⅰ시험)화각막형광소염색검사,병관찰술후haze화굴광회퇴정황,대상관수거진행t검험화상관통계분석.결과 술후1개월87근(23.6%)출현0.5급혹1급haze,술후3개월69안(18.8%),술후6개월48안(13.0%).술후6개월37안(10.1%)출현굴광회퇴.출현haze화굴광회퇴적병례균속우고도근시조.저중도근시조화고도근시조술후BUT치균유불동정도감소.술후1、3、6개월,고도근시조적BUT하강정도교저중도근시조명현,차이유통계학의의(t=6.82、7.51、6.73,P균＜0.05).저중도근시조화고도근시조루액분비량술후여술전상비차이균무통계학의의,술후량조지간루액분비량차이역무통계학의의.술후1、3、6개월,고도근시조각막형광소염색점적수량명현다우저중도근시조(t=5.48、5.23、7.67,P균＜0.05).술후1、3、6개월,고도근시조중haze적발생여BUT하강폭도화각막형광소염색점적수량정정상관(r=0.892、0.881,P균＜0.05).술후6개월,고도근시조굴광회퇴안적BUT치하강폭도교무굴광회퇴안경명현,차이유통계학의의(t=5.50,P＜0.05);굴광회퇴안각막형광소염색점적수량명현다우무굴광회퇴안(t=5.27,P＜0.05).결론 Epi-LASIK술후루막화안표변화여haze급굴광회퇴밀절상관.
Objective To investigate the changes in tear film and ocular surface after epipolis laser in situ keratomileusis (Epi-LASIK), and to evaluate the relationship with haze and refractive regression. Methods Epi-LASIK was performed on 214 eyes with low and moderate myopia and 154 eyes with high myopia. Tear film break up time (BUT), Schirmer Ⅰ test and corneal fluorescence staining were observed before and after the operation. Corneal haze and refractive regression were also examined. The results were analyzed with t test and correlation analysis. Results Haze was found in 87 eyes (23.6%) 1 month after the operation, in 69 eyes (18.8%) 3 months after the operation, and in 48 eyes (13.0%) 6 months after the operation. Refractive regression was found in 37 eyes (10.1%) 6 months after the operation. Haze and refractive regression were only found in high myopia. The values of BUT decreased in all eyes after Epi-LASIK. There was a significant decrease in eyes with high myopia 1 month, 3 months and 6 months after the operation (t=6.82, 7.51,6.73, P＜0.05). The Schirmer Ⅰ test showed no differences when all eyes were compared before and after the operation, and there were no differences between the two groups after the operation (P＞0.05). There was more fluorescence staining on the corneas of eyes with high myopia compared to eyes with low and moderate myopia (t=5.48, 5.23, 7.67, P＜0.05). There was a positive correlation between the occurrence of haze and a decrease in the scope of BUT (r=0.892), and there was a positive correlation between the occurrence of haze and the amount of fluorescence staining on the cornea after the operation (r=0.881). There was a greater decrease in tear film stability in eyes with refractive regression 6 months after the operation (t=5.50, P＜0.05). Theamount of fluorescence staining on the cornea was also greater in eyes with refractive regression 6 months after the operation (t=5.27, P＜0.05). Conclusion The changes in tear film and the ocular surface are associated with haze and refractive regression.
