中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2012年
5期
480-482
,共3页
林晖莉%余江水%李美美%林铮
林暉莉%餘江水%李美美%林錚
림휘리%여강수%리미미%림쟁
脉搏波传导速度%糖尿病%心力衰竭
脈搏波傳導速度%糖尿病%心力衰竭
맥박파전도속도%당뇨병%심력쇠갈
Pulse wave velocity%Diabetes mellitus%Heart failure
目的 探讨2型糖尿病患者的心脏舒张功能和外周动脉脉搏波传导速度(PWV)之间的关系.方法 选取55例2型糖尿病患者,进行心脏彩超、血清B型钠尿肽(BNP)和外周动脉的PWV的检测,根据超声、血清BNP检测结果分成舒张功能正常组33例和舒张功能不全组22例,另取30名健康者作为对照组,比较3组的PWV,并分析超声二尖瓣血流舒张早期峰值速度(E)与瓣环舒张早期峰值速度(E’)的比值(E/E’)与PWV、BNP与PWV的相关性.结果 舒张功能不全的患者动脉PWV较其余两组明显增高[ (770.00±82.11)、(1080.00±158.27)、(1780.00±288.44) cm/s,F =481.605,P＜0.05).调整年龄、性别、血压和血脂后,相关性分析显示E/E’与PWV、BNP与PWV均呈正相关(r=0.58,P＜0.01;r=0.63,P＜0.05).结论 PWV可相应地反映2型糖尿病患者的心脏舒张功能,PWV可作为一种无创性临床指标提示早期舒张性心力衰竭的存在.
目的 探討2型糖尿病患者的心髒舒張功能和外週動脈脈搏波傳導速度(PWV)之間的關繫.方法 選取55例2型糖尿病患者,進行心髒綵超、血清B型鈉尿肽(BNP)和外週動脈的PWV的檢測,根據超聲、血清BNP檢測結果分成舒張功能正常組33例和舒張功能不全組22例,另取30名健康者作為對照組,比較3組的PWV,併分析超聲二尖瓣血流舒張早期峰值速度(E)與瓣環舒張早期峰值速度(E’)的比值(E/E’)與PWV、BNP與PWV的相關性.結果 舒張功能不全的患者動脈PWV較其餘兩組明顯增高[ (770.00±82.11)、(1080.00±158.27)、(1780.00±288.44) cm/s,F =481.605,P＜0.05).調整年齡、性彆、血壓和血脂後,相關性分析顯示E/E’與PWV、BNP與PWV均呈正相關(r=0.58,P＜0.01;r=0.63,P＜0.05).結論 PWV可相應地反映2型糖尿病患者的心髒舒張功能,PWV可作為一種無創性臨床指標提示早期舒張性心力衰竭的存在.
목적 탐토2형당뇨병환자적심장서장공능화외주동맥맥박파전도속도(PWV)지간적관계.방법 선취55례2형당뇨병환자,진행심장채초、혈청B형납뇨태(BNP)화외주동맥적PWV적검측,근거초성、혈청BNP검측결과분성서장공능정상조33례화서장공능불전조22례,령취30명건강자작위대조조,비교3조적PWV,병분석초성이첨판혈류서장조기봉치속도(E)여판배서장조기봉치속도(E’)적비치(E/E’)여PWV、BNP여PWV적상관성.결과 서장공능불전적환자동맥PWV교기여량조명현증고[ (770.00±82.11)、(1080.00±158.27)、(1780.00±288.44) cm/s,F =481.605,P＜0.05).조정년령、성별、혈압화혈지후,상관성분석현시E/E’여PWV、BNP여PWV균정정상관(r=0.58,P＜0.01;r=0.63,P＜0.05).결론 PWV가상응지반영2형당뇨병환자적심장서장공능,PWV가작위일충무창성림상지표제시조기서장성심력쇠갈적존재.
Objective To evaluate the relationship between the heart diastolic function and pulse wave velocity in patients with diabetes mellitus.Methods Fifty-five patients with diabetes mellitus underwent echocardiogram exam,PWV,and BNP determination.Patients were divided into two groups according to the results:the group with normal heart diastolic function(n =33)and the group with abnormal heart diastolic function( n =22).Another 30 healthy volunteers served as control group.The values of PWV were compared.between the three groups.The relationship between E/E' and PWV,BNP and PWV were evaluated with correlation analysis.Results The PWV value of abnormal heart diastolic function group was significantly higher than that of other two groups.PWV was positively correlated with E/E'and BNP ( r =0.58,P ＜ 0.05 ; r =0.63,P ＜ 0.05).Conclusion PWV is associated with the heart diastolic function.PWV can serve as an important factor to predict abnormal heart diastolic function in patients with diabetes mellitus.
