中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2011年
11期
1164-1167
,共4页
尹恝%周亮%吕田明%朱佳佳%曾国利
尹恝%週亮%呂田明%硃佳佳%曾國利
윤괄%주량%려전명%주가가%증국리
原发性头痛%经颅多普勒超声%脑电图%焦虑
原髮性頭痛%經顱多普勒超聲%腦電圖%焦慮
원발성두통%경로다보륵초성%뇌전도%초필
Primary headache%Transeranial Doppler ultrasonography%EEG%Depression
目的 探讨难以分类的原发性头痛患者的临床特点及可能的发病机制.方法 南方医科大学南方医院神经内科自2008年8月至2011年3月收治难以分类原发性头痛患者112例,在发作期行经颅多普勒超声(TCD)、脑电图(EEG)以及汉密顿焦虑量表(HAMA)检查,分析TCD显示的血流速度异常、EEG异常与HAMA评分的关系.结果 TCD检测显示脑血流速度异常81例(72.3％)；EEG检查发现脑电活动异常31例(27.7％),其中轻度异常25例(22.3％),中度异常6例(5.3％)；HAMA量表检测显示＜7分43例(38.4％),7～14分33例(29.5％),＞14分36例(32.1％).无论在TCD显示血流速度异常还是正常情况下,EEG正常与异常患者HAMA评分比较差异均无统计学意义(P＞0.05).无论在EEG异常还是正常情况下,TCD显示正常与异常患者HAMA评分的比较差异无统计学意义(P＞0.05).结论 难以分类原发性头痛与精神和心理疾病共存的情况不可忽视,且颅内血流动力学也有一定程度的变化.对于此类患者,给予改善情绪和调节血流动力学的药物可能有益.
目的 探討難以分類的原髮性頭痛患者的臨床特點及可能的髮病機製.方法 南方醫科大學南方醫院神經內科自2008年8月至2011年3月收治難以分類原髮性頭痛患者112例,在髮作期行經顱多普勒超聲(TCD)、腦電圖(EEG)以及漢密頓焦慮量錶(HAMA)檢查,分析TCD顯示的血流速度異常、EEG異常與HAMA評分的關繫.結果 TCD檢測顯示腦血流速度異常81例(72.3％)；EEG檢查髮現腦電活動異常31例(27.7％),其中輕度異常25例(22.3％),中度異常6例(5.3％)；HAMA量錶檢測顯示＜7分43例(38.4％),7～14分33例(29.5％),＞14分36例(32.1％).無論在TCD顯示血流速度異常還是正常情況下,EEG正常與異常患者HAMA評分比較差異均無統計學意義(P＞0.05).無論在EEG異常還是正常情況下,TCD顯示正常與異常患者HAMA評分的比較差異無統計學意義(P＞0.05).結論 難以分類原髮性頭痛與精神和心理疾病共存的情況不可忽視,且顱內血流動力學也有一定程度的變化.對于此類患者,給予改善情緒和調節血流動力學的藥物可能有益.
목적 탐토난이분류적원발성두통환자적림상특점급가능적발병궤제.방법 남방의과대학남방의원신경내과자2008년8월지2011년3월수치난이분류원발성두통환자112례,재발작기행경로다보륵초성(TCD)、뇌전도(EEG)이급한밀돈초필량표(HAMA)검사,분석TCD현시적혈류속도이상、EEG이상여HAMA평분적관계.결과 TCD검측현시뇌혈류속도이상81례(72.3％)；EEG검사발현뇌전활동이상31례(27.7％),기중경도이상25례(22.3％),중도이상6례(5.3％)；HAMA량표검측현시＜7분43례(38.4％),7～14분33례(29.5％),＞14분36례(32.1％).무론재TCD현시혈류속도이상환시정상정황하,EEG정상여이상환자HAMA평분비교차이균무통계학의의(P＞0.05).무론재EEG이상환시정상정황하,TCD현시정상여이상환자HAMA평분적비교차이무통계학의의(P＞0.05).결론 난이분류원발성두통여정신화심리질병공존적정황불가홀시,차로내혈류동역학야유일정정도적변화.대우차류환자,급여개선정서화조절혈류동역학적약물가능유익.
Objective To investigate the clinical characteristics and mechanism of unclassified primary headache.Methods One hundred and twelve patients suffered from unclassified primary headache,admitted to our hospital from August 2008 to March 2011,were enrolled.Transcranial Doppler (TCD)ultrasonography,EEG and Hamilton Depression Rating Scale(HDRS)were performed on patients during headache attack.The correlations between both abnormalities of blood flow velocity in TCD and EEG and scores of HDRS were analyzed.Results TCD showed abnormality of cerebral blood flow velocity in 81 patients(77.3％).EEG showed mild abnormality of electrical activity in 25patients(22.3％)and medium abnormality in 6 patients(5.3％).The scores of HDRS in 43 patients (38.4％)were below 7 points,while those in 33 patients(29.5％)were between 7 and 14 points,and those in 36 patients(32.1％)were over 14 points.The scores of HDRS between patients with normal EEG and abnormal EEG showed no significant differences under circumstance that normal/abnormal cerebral blood flow velocity was noted under TCD(P＞0.05); the scores of HDRS between patients with normal TCD and abnormal TCD showed no significant differences under circumstance that normal/abnormal electrical activity was noted under EEG(P＞0.05).Conclusion The patients with unclassified primary headache might have such psychiatric problem as anxiety and cerebral hemodynamic changes.Relevant medicine for these malfunctions could be considered in these patients.
