中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
12期
22-23
,共2页
乳腺癌%骨转移%骨显像%单光子发射计算机断层显像
乳腺癌%骨轉移%骨顯像%單光子髮射計算機斷層顯像
유선암%골전이%골현상%단광자발사계산궤단층현상
Breast cancer%Skeletal metastas%Bone imaging%SPECT
目的 探讨99mTc-MDP骨显像联合CT在乳腺癌术后早期随访中,检测其复发及转移临床价值.方法 对253例术后病理确诊的乳腺癌患者一年后分别进行99mTc-MDP骨显像、CT扫描,计算灵敏度、特异性、准确性以及分析骨转移的特点.结果 253例乳腺癌全身骨显像中,发现复发或转移者122例,发生率为48.2%,99mTc-MDP发现骨转移灶分布以胸部肋骨组最多见(50.9%),其次是脊柱椎体(41.8),骨盆(25.4%),四肢骨(14.5%),颅骨和其他骨骼(9.1%);99mTc-MDP骨显像对骨转移的灵敏度、特异性、准确性分别为93.2%、90.7%、91.3%,CT扫描对复发及转移的灵敏度、特异性、准确性分别为58.2%、87.8%、73.5%.CT联合99mTc-MDP骨显像诊断复发及转移的灵敏度、特异性、准确性分别为93.4%、91.6%、92.5%.结论 乳腺癌骨转移发生率很高,骨转移的发生有一定的规律及特点,99mTc-MDP骨显像联合CT可显著提高乳腺癌术后复发及转移的灵敏度、特异性及准确性,对监测其复发及转移具有重要的临床价值.
目的 探討99mTc-MDP骨顯像聯閤CT在乳腺癌術後早期隨訪中,檢測其複髮及轉移臨床價值.方法 對253例術後病理確診的乳腺癌患者一年後分彆進行99mTc-MDP骨顯像、CT掃描,計算靈敏度、特異性、準確性以及分析骨轉移的特點.結果 253例乳腺癌全身骨顯像中,髮現複髮或轉移者122例,髮生率為48.2%,99mTc-MDP髮現骨轉移竈分佈以胸部肋骨組最多見(50.9%),其次是脊柱椎體(41.8),骨盆(25.4%),四肢骨(14.5%),顱骨和其他骨骼(9.1%);99mTc-MDP骨顯像對骨轉移的靈敏度、特異性、準確性分彆為93.2%、90.7%、91.3%,CT掃描對複髮及轉移的靈敏度、特異性、準確性分彆為58.2%、87.8%、73.5%.CT聯閤99mTc-MDP骨顯像診斷複髮及轉移的靈敏度、特異性、準確性分彆為93.4%、91.6%、92.5%.結論 乳腺癌骨轉移髮生率很高,骨轉移的髮生有一定的規律及特點,99mTc-MDP骨顯像聯閤CT可顯著提高乳腺癌術後複髮及轉移的靈敏度、特異性及準確性,對鑑測其複髮及轉移具有重要的臨床價值.
목적 탐토99mTc-MDP골현상연합CT재유선암술후조기수방중,검측기복발급전이림상개치.방법 대253례술후병리학진적유선암환자일년후분별진행99mTc-MDP골현상、CT소묘,계산령민도、특이성、준학성이급분석골전이적특점.결과 253례유선암전신골현상중,발현복발혹전이자122례,발생솔위48.2%,99mTc-MDP발현골전이조분포이흉부륵골조최다견(50.9%),기차시척주추체(41.8),골분(25.4%),사지골(14.5%),로골화기타골격(9.1%);99mTc-MDP골현상대골전이적령민도、특이성、준학성분별위93.2%、90.7%、91.3%,CT소묘대복발급전이적령민도、특이성、준학성분별위58.2%、87.8%、73.5%.CT연합99mTc-MDP골현상진단복발급전이적령민도、특이성、준학성분별위93.4%、91.6%、92.5%.결론 유선암골전이발생솔흔고,골전이적발생유일정적규률급특점,99mTc-MDP골현상연합CT가현저제고유선암술후복발급전이적령민도、특이성급준학성,대감측기복발급전이구유중요적림상개치.
Objective To evaluate the value of clinical application of the combination of CT and 99mTc-MDP bone scan in the follow-up monitoring of cancer recurrences of the breast cancer patients previously treated with both mastecomy and chemotherapy Methods 253 female breast cancer patients treated with mastectomy and chemotherapy within the past one year were enrolled in this study. All of them underwent CT,99mTc-MDP bone scan. calculation of the sensitivity, specialty, accuracy, were analyzed. Results There were 122 patients had the bone metastasis in 253 patients diagnosed breast cancer. the incidence rate was 48.2% . The thoracic part had the most incident of osseous metastasis(50.9%) ,then the vertebral body(41.8%) ,pelvis(25.4%),limbs bone (14. 5 %), skull and the other parts(9. 1%). The sensitivity, specialty, accuracy of 99mTc-MDP bone scan in determining osseuous metastasis were 93.2% 、90. 7% 、91.3% respectively;The sensitivity, specialty,accuracy of CT in the detection of cancer recurrence were 58. 2% 、87.8% 、73.5% respectively in CT scan.When combining 99mTc-MDP bone scan with CT scan,they were 93.4% 、91.6% 、92.5% respectively. Conclusion The incidence rate of osseous metastasis is very high for the breast cancer patients, and the incidence of the osseous metastasis has definite rules and features. the combination of CT and 99mTc-MDP in the follow-up studies of the breast cancer patients previously treated with both mastectomy and chemotherapy can obtain the higher sensitivity, specialty and accuracy, making a significant contribution to the value of clinical application.
