国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2009年
6期
336-340
,共5页
卟啉类化合物%糖分子%分子识别
卟啉類化閤物%糖分子%分子識彆
계람류화합물%당분자%분자식별
Porphyrin compounds%Sugar molecular,Molecular recognition
目的 研究卟啉化合物对糖分子的分子识别作用.方法 采用荧光滴定法分别对所合成的卟啉化合物及其金属配合物进行糖分子识别研究.结果 通过对其结合常数分析,卟啉化合物及其金属配合物对乳糖的识别作用普遍强于葡萄糖,嵌金属Zn,Fe的卟啉化合物其对糖的结合能力明显强于没有金属配位的卟啉化合物.结论 卟啉化合物及其金属配合物对糖分子具有选择性识别作用.
目的 研究卟啉化閤物對糖分子的分子識彆作用.方法 採用熒光滴定法分彆對所閤成的卟啉化閤物及其金屬配閤物進行糖分子識彆研究.結果 通過對其結閤常數分析,卟啉化閤物及其金屬配閤物對乳糖的識彆作用普遍彊于葡萄糖,嵌金屬Zn,Fe的卟啉化閤物其對糖的結閤能力明顯彊于沒有金屬配位的卟啉化閤物.結論 卟啉化閤物及其金屬配閤物對糖分子具有選擇性識彆作用.
목적 연구계람화합물대당분자적분자식별작용.방법 채용형광적정법분별대소합성적계람화합물급기금속배합물진행당분자식별연구.결과 통과대기결합상수분석,계람화합물급기금속배합물대유당적식별작용보편강우포도당,감금속Zn,Fe적계람화합물기대당적결합능력명현강우몰유금속배위적계람화합물.결론 계람화합물급기금속배합물대당분자구유선택성식별작용.
Objective To study the molecular recognition of porphyrin compounds with carbohydrate molecular. Methods Fluorescent titration method was developed to explore the porphyrin and its metal porphyrin compounds interaction with carbohydrate compounds. Results The binding constants indicated that porphyrin and its metal compounds involved in this experiment could recognize carbohydrate compounds respectively, and interaction with lactose is stronger than glucose; Comparison with free porphyrin, metal ion Zn~(2+) and Fe~(3+) in the core of porphyrin compounds could enhance the binding capability with carbohydrate. Conclusion Porphyrin compounds has selective molecular recognition abilityto sugar molecular.
