CAJ | 학술논문

目的观察血液透析联合血液灌流对慢性肾衰竭(CRF)维持血液透析患者甲状旁腺功能亢进症的疗效.方法选取2006年1月至2009年1月深圳市中医院血液透析患者50例,并随机分为两组:常规血液透析组(HD组)、血液透析联合血液灌流组(HD+HP组).HD组行常规血液透析治疗,每周2～3次,HD+HP组在血液透析的基础上联合血液灌流治疗,每周2～3次血液透析,联合血液灌流1次,比较两组患者治疗前及治疗12周后血清钙(Ca)、磷(P)和血清全段反应性甲状旁腺激素(iPTH)的浓度.结果 HD+HP组患者血清P3+和iPTH下降明显,血清Ca2+增高.结论血液透析联合血液灌流可以明显改善CRF维持血液透析患者的继发甲状旁腺功能亢进,并改善其临床症状.
목적 관찰혈액투석연합혈액관류대만성신쇠갈(CRF)유지혈액투석환자갑상방선공능항진증적료효.방법 선취2006년1월지2009년1월심수시중의원혈액투석환자50례,병수궤분위량조:상규혈액투석조(HD조)、혈액투석연합혈액관류조(HD+HP조).HD조행상규혈액투석치료,매주2～3차,HD+HP조재혈액투석적기출상연합혈액관류치료,매주2～3차혈액투석,연합혈액관류1차,비교량조환자치료전급치료12주후혈청개(Ca)、린(P)화혈청전단반응성갑상방선격소(iPTH)적농도.결과 HD+HP조환자혈청P3+화iPTH하강명현,혈청Ca2+증고.결론 혈액투석연합혈액관류가이명현개선CRF유지혈액투석환자적계발갑상방선공능항진,병개선기림상증상.
Objective To observe the effeet of hemodialysis (HD) combination with hemoperfusion (HP) on chronic renal failure patients with secondary hyperparathyroidism. Methods A total of 50 cases of hemodialysis patients from January 2006 to January 2009 were divided into HD group and HD + HP group. HD group was treated with single HD two or three times per week. HD + HP group was treated with HD two or three times per week in connection with HP one time per week. The serum calcium (Ca), phosphorus (P) and intact parathyroid hormone (iPTH) concentrations were compared at 0 w and 12 w between two groups. Results The levels of serum P and iPTH were significantly decreased while serum Ca was increased in HD + HP group. Conclusions HD combination with HP could significantly increase the blood calcium level in the CRF patients with secondary hyperparathyroidism and improve their clinical symptoms.