CAJ | 학술논문

采用液相吸附法制备了羟基磷灰石/外消旋聚乳酸[hydroxyapatite/poly-D,L(racemic)lactic acid,HA/PDLLA]复合材料,通过材料实验机和体外模拟试验研究了复合材料的力学性能和体外降解性能.对材料的力学测试表明,由于加入了质量分数为10%的HA颗粒,复合材料的力学性能得到了改善,复合材料的弯曲强度达146.2 MPa,弯曲模量为2.5 GPa,与纯PDLLA材料相比,弯曲强度提高了9.4 MPa,弯曲模量提高了0.2 GPa,同时其拉伸强度下降并不明显.体外降解模拟试验结果表明,HA含量为10%的复合材料在前6周的质量损失小于1%,在第12周的最终质量损失为5.4%,其在降解中后期的质量损失比纯PDLLA材料低约2%～3%.
채용액상흡부법제비료간기린회석/외소선취유산[hydroxyapatite/poly-D,L(racemic)lactic acid,HA/PDLLA]복합재료,통과재료실험궤화체외모의시험연구료복합재료적역학성능화체외강해성능.대재료적역학측시표명,유우가입료질량분수위10%적HA과립,복합재료적역학성능득도료개선,복합재료적만곡강도체146.2 MPa,만곡모량위2.5 GPa,여순PDLLA재료상비,만곡강도제고료9.4 MPa,만곡모량제고료0.2 GPa,동시기랍신강도하강병불명현.체외강해모의시험결과표명,HA함량위10%적복합재료재전6주적질량손실소우1%,재제12주적최종질량손실위5.4%,기재강해중후기적질량손실비순PDLLA재료저약2%～3%.
A hydroxyapatite/poly-D, L (racemic) lactic acid (HA/PDLLA) composite was prepared by recombination of liquid-phase adsorption. The mechanical properties of the composite were determined, and the degradation of the composite was investigated via simulation in vitro. Results illustrate that the mechanical properties of the composite are improved with a bending strength of 146.2 Mpa,a bend modulus of 2.5 Gpa, due to the addition of 10％ mass fraction of HA particles into the composite. Compared with pure PDLLA material, the bending strength is increased 9.4 Mpa, the bending modulus is increased 0.2 Gpa, and the decline of the tensile strength of the composite is not obvious. The mass loss of the 90％ PDLLA/10％ HA composite was less than 1％ during the initial 6 weeks, and the fmal mass loss was 5.4％ at the 12th week. The mass loss of the composite was smaller than that of pure PDLLA material by about 2％-3％ in the mid-later period of degradation.