CAJ | 학술논문

　　目的：建立同时测定补骨脂中补骨脂素、异补骨脂素和补骨脂酚3种主要有效成分含量的高效液相色谱方法，比较补骨脂盐炙品炮制前后三种成分含量的变化。方法：采用盐炙法对7个不同地区来源的补骨脂进行炮制，利用高效液相色谱法，甲醇-水梯度洗脱，检测波长246nm，测定炮制前后补骨脂素、异补骨脂素及补骨脂酚的含量。结果：盐炙法使补骨脂中的补骨脂素和异补骨脂素含量增加，使补骨脂酚的含量减少。结论：盐炙法使补骨脂中的三种主要有效成分含量发生了变化。
　　목적：건립동시측정보골지중보골지소、이보골지소화보골지분3충주요유효성분함량적고효액상색보방법，비교보골지염자품포제전후삼충성분함량적변화。방법：채용염자법대7개불동지구래원적보골지진행포제，이용고효액상색보법，갑순-수제도세탈，검측파장246nm，측정포제전후보골지소、이보골지소급보골지분적함량。결과：염자법사보골지중적보골지소화이보골지소함량증가，사보골지분적함량감소。결론：염자법사보골지중적삼충주요유효성분함량발생료변화。
Objective:To establish a quantitative method of determination of psoralen,isopsoralen and bakuchiol in fruits of Psoralea carylifolia. and salt-processed one,and compare changes of the three kinds of component between them. Method:The content of psoralen,isopsoralen and bakuchiol in the salt-processed one from 7 different areas were determined by HPLC-gradient elution, determined on 246nm wavelength. Results:The content of psoralen and isopsoralen in salt-processed one were raising,and the content of bakuchiol was reducing. Conclusions:The method of salt process could change the content of psoralen,isopsoralen and bakuchiol in fruits of Psoralea carylifolia.