国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2009年
4期
447-449
,共3页
张必嘏%杜梅仙%马晓燕%舒方
張必嘏%杜梅仙%馬曉燕%舒方
장필하%두매선%마효연%서방
目的 探索持续性腹膜透析(CAPD)的尿毒症患者使用阿魏酸哌嗪对残余肾功能(RRF)的影响.方法 43例CAPD治疗的尿毒症患者随机分为治疗组与对照组,治疗组22例,对照21例;治疗组在对照组基础上加用中成药阿魏酸哌嚷,每次150mg,每天3次,疗程12个月;观察治疗前、后的血压(BP)、体重(BW)、血色素(Hb)、血尿素氮(BUN)、肌酐(Scr)、血白蛋白(Alb)等指标;分别检测二组治疗6、12、18个月的RRF及尿量.结果 与对照组相比,治疗后的治疗组RRF下降速度减慢(P＜0.05).尿量减少明显减缓(p＜0.01),BP控制对照组满意(p＜0.05).Hb、BW、Alb好于对照组(P＜0.05～0.01).结论 阿魏酸哌嗪对CAPD尿毒症患者的RRF有保护作用,延缓尿量的减少,改善患者营养,提高CAPD患者的生活质量.
目的 探索持續性腹膜透析(CAPD)的尿毒癥患者使用阿魏痠哌嗪對殘餘腎功能(RRF)的影響.方法 43例CAPD治療的尿毒癥患者隨機分為治療組與對照組,治療組22例,對照21例;治療組在對照組基礎上加用中成藥阿魏痠哌嚷,每次150mg,每天3次,療程12箇月;觀察治療前、後的血壓(BP)、體重(BW)、血色素(Hb)、血尿素氮(BUN)、肌酐(Scr)、血白蛋白(Alb)等指標;分彆檢測二組治療6、12、18箇月的RRF及尿量.結果 與對照組相比,治療後的治療組RRF下降速度減慢(P＜0.05).尿量減少明顯減緩(p＜0.01),BP控製對照組滿意(p＜0.05).Hb、BW、Alb好于對照組(P＜0.05～0.01).結論 阿魏痠哌嗪對CAPD尿毒癥患者的RRF有保護作用,延緩尿量的減少,改善患者營養,提高CAPD患者的生活質量.
목적 탐색지속성복막투석(CAPD)적뇨독증환자사용아위산고진대잔여신공능(RRF)적영향.방법 43례CAPD치료적뇨독증환자수궤분위치료조여대조조,치료조22례,대조21례;치료조재대조조기출상가용중성약아위산고양,매차150mg,매천3차,료정12개월;관찰치료전、후적혈압(BP)、체중(BW)、혈색소(Hb)、혈뇨소담(BUN)、기항(Scr)、혈백단백(Alb)등지표;분별검측이조치료6、12、18개월적RRF급뇨량.결과 여대조조상비,치료후적치료조RRF하강속도감만(P＜0.05).뇨량감소명현감완(p＜0.01),BP공제대조조만의(p＜0.05).Hb、BW、Alb호우대조조(P＜0.05～0.01).결론 아위산고진대CAPD뇨독증환자적RRF유보호작용,연완뇨량적감소,개선환자영양,제고CAPD환자적생활질량.
Objectives To investigate the effect Pipeazime Feyulate on residual renal function (FFR) in continuons ambulatory peritoneal dialysis(CAPD) patients. Methods Fourty - three patients of uremia were randomly divided into two gronps. 22 patients in the treated group and 21 patients in the control group. All patients were treated by continuous ambulatory peritoneal dialysis (CAPD). The patients of the treated gronp combined with Pipperazine ferulate 150mg3times per day. The therapeutic course were 18months. The change in general condition blood pressure(BP) ,body weight(BW), hemoglobin(lib), blood ures nitrogen (BUN) ,serum creatinine(Scr) albumin(Alb) before and after treatment were observed. RRF and amount of urine measured before and after 6,12,18 months treatment respectively. Results In the treated groyp, after treatment,the decline of RRF and amount of urine were significantly slower than those in the control group(p ＜0.05) ,also the levels of Bp in former were markedly better than later group(p ＜0.05) ,significant improvement were revealed in aspects of Hb,BW,Alb in the treated stop(p ＜0.05 -0.01). Conclusions Piperazine Ferulate was effective in slowing domn the decrease of RRF and amount of urine,improving nutritional condition and quality of life in patients of uremia treated by CAPD.
