中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2009年
7期
1215-1216
,共2页
陈娇莲%黄楚卿%钟伟润%陈平湖
陳嬌蓮%黃楚卿%鐘偉潤%陳平湖
진교련%황초경%종위윤%진평호
血红蛋白指数%大肠病变%结肠镜检查%微血管密度
血紅蛋白指數%大腸病變%結腸鏡檢查%微血管密度
혈홍단백지수%대장병변%결장경검사%미혈관밀도
Index of hemoglobin%Colorectal lesions%Colonoscopy%Microvessel density
目的 探讨血红蛋白指数(IHb)色图测定对大肠病变的诊断价值.方法 采用电子肠镜对267例患者进行观察,在选择的相应区域记录IHb色图,并取活检组织行病理学检查,同时采用免疫组织化学染色方法 计数微血管密度(MVD).结果 与周边黏膜相比,炎性息肉及腺瘤性息肉IHb值高,而增生性息肉IHb值比周边稍低或差别不大,但比炎性息肉IHb值低(P<0.01);炎症浸润重的黏膜IHb值比正常黏膜高(P<0.05);肿瘤的IHb值多明显高于癌周黏膜,高分化腺癌的IHb值高于低分化腺癌(P<0.05);IHb值高的区域其MVD也较高(P<0.01).结论 结肠镜下IHb色图测定操作简单,对病灶性质的判断、病灶范围的确定、微小病灶的检出和指导内镜治疗有一定的临床意义.
目的 探討血紅蛋白指數(IHb)色圖測定對大腸病變的診斷價值.方法 採用電子腸鏡對267例患者進行觀察,在選擇的相應區域記錄IHb色圖,併取活檢組織行病理學檢查,同時採用免疫組織化學染色方法 計數微血管密度(MVD).結果 與週邊黏膜相比,炎性息肉及腺瘤性息肉IHb值高,而增生性息肉IHb值比週邊稍低或差彆不大,但比炎性息肉IHb值低(P<0.01);炎癥浸潤重的黏膜IHb值比正常黏膜高(P<0.05);腫瘤的IHb值多明顯高于癌週黏膜,高分化腺癌的IHb值高于低分化腺癌(P<0.05);IHb值高的區域其MVD也較高(P<0.01).結論 結腸鏡下IHb色圖測定操作簡單,對病竈性質的判斷、病竈範圍的確定、微小病竈的檢齣和指導內鏡治療有一定的臨床意義.
목적 탐토혈홍단백지수(IHb)색도측정대대장병변적진단개치.방법 채용전자장경대267례환자진행관찰,재선택적상응구역기록IHb색도,병취활검조직행병이학검사,동시채용면역조직화학염색방법 계수미혈관밀도(MVD).결과 여주변점막상비,염성식육급선류성식육IHb치고,이증생성식육IHb치비주변초저혹차별불대,단비염성식육IHb치저(P<0.01);염증침윤중적점막IHb치비정상점막고(P<0.05);종류적IHb치다명현고우암주점막,고분화선암적IHb치고우저분화선암(P<0.05);IHb치고적구역기MVD야교고(P<0.01).결론 결장경하IHb색도측정조작간단,대병조성질적판단、병조범위적학정、미소병조적검출화지도내경치료유일정적림상의의.
Objective To evaluate the value of IHb map in colorectal lesions. Methods IHb map images was observed in 267 patients with colorectal lesions using colonoscopy. Biopsies were taken and microvessel density (MVD) were examined by immunohistochemical staining. Results Colorectal polyps were found in 133 patient,IHb values were higher in inflammatory and adenomatous polyps,and IHb values of hyperplastic polyps were significantly lower than that of inflammatory polyps(P < 0.01). IHb values were higher in the specimens of more inflammatory cell infiltration than normal mucosa (P < 0.05). IHb values seemed to be related to tumor differentiation. An increased IHb values was more frequently observed in differentiated carcinoma than in undifferentiated carcinoma(P < 0.05). The higher of IHb values, the higher of MVD (P < 0.01). Conclusion To oporate IHb map is simple, measurement of IHb map is useful in detecting minimal lesion in colorectal lesions,distingnishing the benign from the malignant,de-termining the extent of the lesion and do endoscopic treatment timely.
