CAJ | 학술논문

目的探讨脑电双频指数(BIS)在儿科ICU危重患儿镇静深度监测中的应用价值.方法前瞻性收集我院PICU的42例6个月～13岁的危重患儿,以咪唑安定持续静脉滴注镇静治疗,在应用镇静剂后的10个时间段以Ramsay评分评价镇静深度的同时进行BIS监测,分析BIS与Ramsay评分在儿童危重症镇静评估的相关性及影响因素.结果 42例危重症患儿中共采集420对BIS与Ramsay对照数据,并做Spearman等级相关分析,BIS与Ramsay评分呈明显负相关(r=-0.8879,P<0.01);在6个月～1岁患儿数据分析中,BIS与Ramsay评分无相关性(r=0.842 7,P>0.05);BIS范围在55～80之间为危重症患儿合适的镇静分值.结论 BIS与Ramsay评分在危重症镇静深度评估中具有较好相关性.BIS监测具有操作简单、省时、连续性好等优点,可作为PICU患儿镇静深度判断的客观指标.
목적 탐토뇌전쌍빈지수(BIS)재인과ICU위중환인진정심도감측중적응용개치.방법 전첨성수집아원PICU적42례6개월～13세적위중환인,이미서안정지속정맥적주진정치료,재응용진정제후적10개시간단이Ramsay평분평개진정심도적동시진행BIS감측,분석BIS여Ramsay평분재인동위중증진정평고적상관성급영향인소.결과 42례위중증환인중공채집420대BIS여Ramsay대조수거,병주Spearman등급상관분석,BIS여Ramsay평분정명현부상관(r=-0.8879,P<0.01);재6개월～1세환인수거분석중,BIS여Ramsay평분무상관성(r=0.842 7,P>0.05);BIS범위재55～80지간위위중증환인합괄적진정분치.결론 BIS여Ramsay평분재위중증진정심도평고중구유교호상관성.BIS감측구유조작간단、성시、련속성호등우점,가작위PICU환인진정심도판단적객관지표.
Objective To evaluate the applicability of bispectral index (BIS) in assessing sedation in pediatric intensive care unit. Methods Patients in pediatric ICU,aged six months to thirteen years and requi-ring sedation were given midazolam as sedative drug. The Ramsay score was assessed by physicians after mi-dazolam was given at ten time interval and these data were compared with the blinded BIS score. Results A total of 42 children were included in the study,420 valid paired observation of BIS values and Ramsay score were performed. According to Spearman's scale analysis, the correlation coefficient between BIS value and Ramsay score was -0.887 9 (P<0.01). But the correlation coefficient between BIS value and Ramsay score in the small age group(age from 6 months to 1 year) was 0.842 7 (P>0.05). Conclusion BIS values cor-relate fairly well with the Ramsay scores in PICU patient. With the advantages such as simpleness, time-sav-ing,continuity and etc,BIS monitoring is a good objective tool for judging sedation depth of PICU patients.