CAJ | 학술논문

目的: 定性定量分析藤黄中的xanthone类化合物.方法:应用一种简便快捷的高效液相色谱方法.结果:从藤黄药材中鉴定出其中xanthone类主要成分:isomorellic acid (1),morellic acid (2),isogambogenic acid (3),gambogenic acid (5),isogambogic acid (6),gambogic acid (7) and 30-hydroxygambogic acid (4),并进行了有关的定量分析.同时对采自中国及印度不同地区的7份藤黄药材进行了HPLC色谱分析,以上述其中xanthone类化合物为指标成分,对藤黄药材的HPLC色谱特征进行了描述.结论:该方法简便快捷,能有效地应用到藤黄药材的质量控制中.
목적: 정성정량분석등황중적xanthone류화합물.방법:응용일충간편쾌첩적고효액상색보방법.결과:종등황약재중감정출기중xanthone류주요성분:isomorellic acid (1),morellic acid (2),isogambogenic acid (3),gambogenic acid (5),isogambogic acid (6),gambogic acid (7) and 30-hydroxygambogic acid (4),병진행료유관적정량분석.동시대채자중국급인도불동지구적7빈등황약재진행료HPLC색보분석,이상술기중xanthone류화합물위지표성분,대등황약재적HPLC색보특정진행료묘술.결론:해방법간편쾌첩,능유효지응용도등황약재적질량공제중.
AIM: To characterize and quantitatively analyze the xanthones in gamboges. METHOD: A simple and rapid HPLC method was used. RESULTS: Seven major xanthones of gamboges were characterized to be isomorellic acid (1), morellic acid (2), isogambogenic acid (3), gambogenic acid (5), isogambogic acid (6), gambogic acid (7), and 30-hydroxygambogic acid (4) by LC/ESI-MS, respectively. The validation of the quantitative method was performed accordingly. Seven samples from different regions of China and India were examined.They showed similar chromatographic patterns in the HPLC fingerprints, containing the above-mentioned seven major constituents as the characteristic markers. The relative retention time and relative peak area of these characteristic peaks were calculated and set as important parameters for the fingerprinting identification of gamboges. CONCLUSION: This is a simple, rapid, and efficient quality-control method for the gamboges.