CAJ | 학술논문

利用粒径分布为0.27～1.70 mm的煤质颗粒活性炭为吸附剂,采用固定床方式分离废弃液中的去乙酰头孢菌素C(DCPC).以8%(体积)乙醇水溶液洗脱,得到DCPC纯度大于85%的洗脱液,收率为60%～65%.洗脱液经过纳滤膜浓缩后,通过阴离子交换树脂Amberlite IRA67吸附,以0.5 mol·L~(-1)醋酸钠缓冲液(pH6.3)洗脱,得到DCPC纯度96%、含量大于30 g·L~(-1)的去乙酰头孢菌素C的钠盐溶液,收率在90%～95%.加入丙酮,可得到去乙酰头孢菌素C钠盐结晶.以含有异丙醇的强碱溶液浸泡洗涤洗脱后的煤质颗粒活性炭,再用酸溶液中和冲洗,可恢复其吸附能力.
이용립경분포위0.27～1.70 mm적매질과립활성탄위흡부제,채용고정상방식분리폐기액중적거을선두포균소C(DCPC).이8%(체적)을순수용액세탈,득도DCPC순도대우85%적세탈액,수솔위60%～65%.세탈액경과납려막농축후,통과음리자교환수지Amberlite IRA67흡부,이0.5 mol·L~(-1)작산납완충액(pH6.3)세탈,득도DCPC순도96%、함량대우30 g·L~(-1)적거을선두포균소C적납염용액,수솔재90%～95%.가입병동,가득도거을선두포균소C납염결정.이함유이병순적강감용액침포세조세탈후적매질과립활성탄,재용산용액중화충세,가회복기흡부능력.
Coal granular activated carbon with particle size distribution from 0.27 mm to 1.70 mm was used as adsorbent in a fixed-bed to separate deacetyl cephalosporin C(DCPC)from the waste drainage.The adsorbed DCPC on the carbon was eluted with 8%(vol)ethanol aqueous solution,and the obtained eluate contained DCPC in a yield of 60%～65% with a purity higher than 85% .After being further condensed through nanofilter membrane,the eluate was allowed to pass through anion-exchange resin Amberlite IRA67 on which DCPC was adsorbed.Desorption with 0.5 mol·L~(-1) sodium acetate buffer solution(pH6.3),DCPC was obtained as sodium salt solution in a yield of 90%～95% with 96% purity and the concentration was higher than 30 g·L~(-1).DCPC sodium salt was isolated by crystallization through adding acetone to the eluate.The adsorption capacity of the used coal granular activated carbon could be restored by saturation with alkali solution containing isopropanol and then neutralization with acidic solution.