CAJ | 학술논문

目的观察芪苈强心胶囊对慢性心力衰竭患者运动耐量的影响.方法将入选的86例慢性心力衰竭患者,随机分为治疗组和对照组,均给与血管紧张素转化酶抑制剂(ACEI)类、利尿剂、卡维地洛或倍他乐克和地戈辛等常规治疗,治疗组在常规治疗基础上加服芪苈强心胶囊4粒,3次/d.观察4周后患者运动耐量及左室射血分数(LVEF)的变化.结果治疗后两组6min步行试验距离增加(P均＜0.05),且治疗组增加明显(P＜0.05).治疗后两组LVEF均提高(P均＜0.05).治疗组显效率、总有效率均高于对照组(P均＜0.05).结论芪苈强心胶囊联合常规西药,可有效增加患者的运动耐量、改善心功能.
목적 관찰기력강심효낭대만성심력쇠갈환자운동내량적영향.방법 장입선적86례만성심력쇠갈환자,수궤분위치료조화대조조,균급여혈관긴장소전화매억제제(ACEI)류、이뇨제、잡유지락혹배타악극화지과신등상규치료,치료조재상규치료기출상가복기력강심효낭4립,3차/d.관찰4주후환자운동내량급좌실사혈분수(LVEF)적변화.결과 치료후량조6min보행시험거리증가(P균＜0.05),차치료조증가명현(P＜0.05).치료후량조LVEF균제고(P균＜0.05).치료조현효솔、총유효솔균고우대조조(P균＜0.05).결론 기력강심효낭연합상규서약,가유효증가환자적운동내량、개선심공능.
Objective To investigate the influence of Qiliqiangxin capsule on the exercise tolerance in patients with chronic heart failure. Methods 86 patients with chronic heart failure were selected and recruited into a control group and an observation group randomly. The patients in the control group were given angiotensin-converting enzyme inhibitor, diuretic,carvedilol or metoprolol and dixina. The patients in the observation group were given Qiliqiangxin capsule on the basis of the control group. The change of exercise tolerance and left ventricular ejection fraction in all patients were detected after 4 weeks.Results The distance of walking in 6 minutes increased for all patients after 4 weeks' treatment(P＜0.05), while the observation group increased more significantly than the control group(P＜0.05). The left ventricular ejection fraction increased for all patients after therapy 4 weeks (P＜0.05), while the observation group increased more obviously than the control group (P＜0.05). The total excellent rate and effective rate in the observation group were both higher than the control group (P＜0.05). Conclusion Qiliqiangxin capsule can increase the clinic curative effect by increasing the exercise tolerance and improving the heart function of patients with chronic heart failure.