药学学报
藥學學報
약학학보
ACTA PHARMACEUTICA SINICA
2006年
4期
370-375
,共6页
易涛%詹先成%李成容%何宁
易濤%詹先成%李成容%何寧
역도%첨선성%리성용%하저
高精度散射光度滴定法%苯妥英钠%溶度积常数%凝胶
高精度散射光度滴定法%苯妥英鈉%溶度積常數%凝膠
고정도산사광도적정법%분타영납%용도적상수%응효
highly accurate nephelometric titration%phenytoin sodium%solubility product constant%colloid
目的用高精度散射光度滴定法测定苯妥英钠.方法测定了苯妥英银凝胶的溶度积常数,研究了滴定的最优条件.结果滴定结果与对照试验测定结果无显著差异.结论用高精度散射光度滴定法测定苯妥英钠结果准确、重复性好、专属性强、线性范围宽.
目的用高精度散射光度滴定法測定苯妥英鈉.方法測定瞭苯妥英銀凝膠的溶度積常數,研究瞭滴定的最優條件.結果滴定結果與對照試驗測定結果無顯著差異.結論用高精度散射光度滴定法測定苯妥英鈉結果準確、重複性好、專屬性彊、線性範圍寬.
목적용고정도산사광도적정법측정분타영납.방법측정료분타영은응효적용도적상수,연구료적정적최우조건.결과적정결과여대조시험측정결과무현저차이.결론용고정도산사광도적정법측정분타영납결과준학、중복성호、전속성강、선성범위관.
Aim To determine phenytoin sodium by a highly accurate nephelometric titration.Methods The titration operating conditions were optimized and the solubility product constant of phenytoin silver precipitation was determined. Results The result of the titration is comparable to those of control experiments. Conclusion The proposed method has been found to be accurate, precise, specific,reproducible, and linear.
