CAJ | 학술논문

B7-H4是共刺激分子B7家族的新成员,B7-H4通过抑制T细胞的增殖、细胞因子的产生和细胞周期的进行对T细胞免疫进行负调控.近期研究表明,B7-H4与肿瘤的发生发展有着密切关系,是肿瘤诊断和治疗的重要指标.
B7-H4시공자격분자B7가족적신성원,B7-H4통과억제T세포적증식、세포인자적산생화세포주기적진행대T세포면역진행부조공.근기연구표명,B7-H4여종류적발생발전유착밀절관계,시종류진단화치료적중요지표.
B7-H4 is a new member of costimulatory molecules,it negatively regulates T cell immunity by the inhibition of T cell proliferation, cytokine production, and cell cycle progression. Recent studies indicate that B7- H4 is associated with the generation and progression of tumor and is an important indication in the diag-nosis and treatment of tumor.