CAJ | 학술논문

目的探讨胃血吸虫病与胃癌的相关性.方法对11例胃血吸虫病患者的临床资料进行回顾性分析.结果胃血吸虫病并发胃癌的比例为54.5％(6/11),其中高、中分化腺癌占83.3％( 5/6)；虫卵沉积处的黏膜有明显肠上皮化生、腺体增生、异型上皮灶及中至重度不典型增生等病理改变.结论胃血吸虫病可显著提高胃癌的发病几率.胃血吸虫病无特征性表现,症状与慢性胃炎酷似.因此,生活于血吸虫病疫区并有类似慢性胃炎的患者,需要增加在胃窦幽门区及小弯侧的活检次数,一旦确诊为胃血吸虫病的患者,要定期接受胃镜检查以监控胃癌的发生.
목적 탐토위혈흡충병여위암적상관성.방법 대11례위혈흡충병환자적림상자료진행회고성분석.결과 위혈흡충병병발위암적비례위54.5％(6/11),기중고、중분화선암점83.3％( 5/6)；충란침적처적점막유명현장상피화생、선체증생、이형상피조급중지중도불전형증생등병리개변.결론위혈흡충병가현저제고위암적발병궤솔.위혈흡충병무특정성표현,증상여만성위염혹사.인차,생활우혈흡충병역구병유유사만성위염적환자,수요증가재위두유문구급소만측적활검차수,일단학진위위혈흡충병적환자,요정기접수위경검사이감공위암적발생.
Objective To investigate the relationship between gastrc schistosomiasis and gastrc cancer.Methods The data of 11 cases of gastrc schistosomiasis were retrospective analyzed.Results 54.5％ (6/11) of gastrc schistosomiasis cases complicated with gastrc cancer,and 83.3％ (5/6) was well-differentiated and moderately differentiated.Seen around the parasite eggs were obvious intestinal metaplasia,gland hyperplasia,abnormal epithelial lesions and other serious atypical hyperplasia.Conclusions Gastric schistosomiasis significantly increases the risk of gastrc cancer.Gnstrc schistosomiasis does not have specific symptoms,and it is clinically sumilar to chronic gastrtis.Therefore,patients with chronic gastrtis-like symptoms in the schistosomiasis endemic areas should be subjected to an intensive test for gastrc schistosomiasis in the biopsy specimens collected from pyloric antrum and gastric lesser curvature.Patients infected by gastric schistosomiasis are strongly suggested to go regularly for gastric cancer check with gastroscopy.