CAJ | 학술논문

目的探讨破裂颅内动脉瘤经血管内栓塞治疗后症状性脑血管痉挛的发生及相关因素。方法河南大学附属南石医院神经外科自2008年5月至2010年1月应用电解可脱性弹簧圈栓塞治疗破裂动脉瘤78例，回顾性分析患者的临床资料，判定症状性脑血管痉挛的发生并分析其影响因素。结果本组78例患者栓塞治疗均成功，术后出现症状性脑血管痉挛20例(25.6％)，不同Hunt-Hess分级、Fisher分级患者术后症状性脑血管痉挛的发生率差异有统计学意义(P＜0.05)。经积极治疗后14例恢复正常,3例中度致残，3例放弃治疗。结论栓塞治疗破裂动脉瘤后症状性血管痉挛的发生与神经功能损害和出血量大小有关，腰大池引流对降低血管痉挛发生有积极意义。
목적탐토파렬로내동맥류경혈관내전새치료후증상성뇌혈관경련적발생급상관인소。 방법하남대학부속남석의원신경외과자2008년5월지2010년1월응용전해가탈성탄황권전새치료파렬동맥류78례，회고성분석환자적림상자료，판정증상성뇌혈관경련적발생병분석기영향인소。 결과본조78례환자전새치료균성공，술후출현증상성뇌혈관경련20례(25.6％)，불동Hunt-Hess분급、Fisher분급환자술후증상성뇌혈관경련적발생솔차이유통계학의의(P＜0.05)。경적겁치료후14례회복정상,3례중도치잔，3례방기치료。 결론전새치료파렬동맥류후증상성혈관경련적발생여신경공능손해화출혈량대소유관，요대지인류대강저혈관경련발생유적겁의의。
Objective To investigate the incidence of symptomatic cerebral vasospasm in patients with ruptured intracranial aneurysms after embolization and its correlative factors. Methods The clinical data of 78 patients with ruptured intracranial aneurysms after embolization, admitted to our hospital from May 2008 to January 2010, were retrospectively analyzed. The occurrence of symptomatic cerebral vasospasm was assessed and its influencing factors were analyzed. Results The embolization of these 78 patients was successful. Postoperative symptomatic cerebral vasospasm occurred in 20patients (25.6％). Significant differences in the incidence of cerebral vasospasm among patients of different Hunt-Hess grades, Fisher grades were noted (P＜0.05). Fourteen patients were back to normal and 3 had moderate disability after proper treatment,while the other 3 gave up treatment. Conclusion The occurrence of symptomatic cerebral vasospasm of patients with ruptured aneurysm atter embolization may be associated with the neurological damage degree and amount of bleeding. Lumbar drainage can positively reduce the incidence of cerebral vasospasm.