中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
13期
57-60
,共4页
泌尿系感染%病原菌%分布%耐药性
泌尿繫感染%病原菌%分佈%耐藥性
비뇨계감염%병원균%분포%내약성
Urinary tract infection%Pathogens%Distribution%Resistance
目的 研究泌尿系感染病原菌的分布情况及耐药现状,为临床合理用药提供依据.方法 用常规方法时2007年1月至2011年12月河源市人民医院门诊/住院泌尿系感染患者的中段尿标本进行细菌培养,全自动微生物鉴定药敏仪Walkaway 40对细菌进行鉴定和药敏试验,应用Whonet 5.4软件进行数据统计.结果 分离出502株病原菌中革兰氏阴性菌358株(71.3％),革兰氏阳性球菌116株(23.1％),真菌28株(5.6％).革兰氏阴性菌中以大肠埃希菌为主,占49.4％,产超广谱β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌检出率分别为35.5％和37.5％；革兰氏阳性球菌主要是粪肠球菌和凝固酶阴性葡萄球菌,分别占11.2％和8.0％,高浓度氨基糖苷类耐药粪肠球菌和耐甲氧西林凝固酶阴性葡萄球菌检出率分别为46.4％和67.5％；真菌主要是白色念珠菌,占3.2％.亚胺培南对革兰氏阴性杆菌耐药率均＜20.0％；呋喃妥因、利奈唑胺、万古霉素对革兰氏阳性球菌耐药率均为0.结论 引起泌尿系感染主要病原菌是大肠埃希菌,其次为粪肠球菌.亚胺培南对革兰氏阴性杆菌有较好的体外抗菌活性,利奈唑胺、呋喃妥因、万古霉素对革兰氏阳性球菌有较好的体外抗菌活性.
目的 研究泌尿繫感染病原菌的分佈情況及耐藥現狀,為臨床閤理用藥提供依據.方法 用常規方法時2007年1月至2011年12月河源市人民醫院門診/住院泌尿繫感染患者的中段尿標本進行細菌培養,全自動微生物鑒定藥敏儀Walkaway 40對細菌進行鑒定和藥敏試驗,應用Whonet 5.4軟件進行數據統計.結果 分離齣502株病原菌中革蘭氏陰性菌358株(71.3％),革蘭氏暘性毬菌116株(23.1％),真菌28株(5.6％).革蘭氏陰性菌中以大腸埃希菌為主,佔49.4％,產超廣譜β-內酰胺酶的大腸埃希菌和肺炎剋雷伯菌檢齣率分彆為35.5％和37.5％；革蘭氏暘性毬菌主要是糞腸毬菌和凝固酶陰性葡萄毬菌,分彆佔11.2％和8.0％,高濃度氨基糖苷類耐藥糞腸毬菌和耐甲氧西林凝固酶陰性葡萄毬菌檢齣率分彆為46.4％和67.5％；真菌主要是白色唸珠菌,佔3.2％.亞胺培南對革蘭氏陰性桿菌耐藥率均＜20.0％；呋喃妥因、利奈唑胺、萬古黴素對革蘭氏暘性毬菌耐藥率均為0.結論 引起泌尿繫感染主要病原菌是大腸埃希菌,其次為糞腸毬菌.亞胺培南對革蘭氏陰性桿菌有較好的體外抗菌活性,利奈唑胺、呋喃妥因、萬古黴素對革蘭氏暘性毬菌有較好的體外抗菌活性.
목적 연구비뇨계감염병원균적분포정황급내약현상,위림상합리용약제공의거.방법 용상규방법시2007년1월지2011년12월하원시인민의원문진/주원비뇨계감염환자적중단뇨표본진행세균배양,전자동미생물감정약민의Walkaway 40대세균진행감정화약민시험,응용Whonet 5.4연건진행수거통계.결과 분리출502주병원균중혁란씨음성균358주(71.3％),혁란씨양성구균116주(23.1％),진균28주(5.6％).혁란씨음성균중이대장애희균위주,점49.4％,산초엄보β-내선알매적대장애희균화폐염극뢰백균검출솔분별위35.5％화37.5％；혁란씨양성구균주요시분장구균화응고매음성포도구균,분별점11.2％화8.0％,고농도안기당감류내약분장구균화내갑양서림응고매음성포도구균검출솔분별위46.4％화67.5％；진균주요시백색념주균,점3.2％.아알배남대혁란씨음성간균내약솔균＜20.0％；부남타인、리내서알、만고매소대혁란씨양성구균내약솔균위0.결론 인기비뇨계감염주요병원균시대장애희균,기차위분장구균.아알배남대혁란씨음성간균유교호적체외항균활성,리내서알、부남타인、만고매소대혁란씨양성구균유교호적체외항균활성.
[Objective] To provide basis for clinical reasonable using medication by investigating pathogens distribution of urinary tract infection and conditions of the drug resistance.[Methods] The midstream urine spceimens were cultured in the cases of urinary tract infection out-patients and hospital patients from January 2007 to December 2011.The identification of bacteria and antibiotic susceptibility test were carried out automatic microbiological system by Walkaway-40,statistical analysis was performed by Whonet 5.4.[Results] Among the 502 pathogenic bacteria isolated,Gram-negative bacteria,Grampositive cocci and Fungus accounted for 71.3％,23.1％ and 5.6％ respectively.Gram-negative bacteria were E.coli primarily,which accounted for 49.4％.Ecoli and K.pneumoniae were 35.5％ and 37.5％ among ESBLs.The main Gram-positive cocci were E.faecalis and coagulase-negative staphylococcus,which accounted for 11.2％ and 8.0％,the detection rates of HLARE and MRCONS were 46.4％ and 67.5％.Fungus predominantly were Candida albicans 3.2％.The resistance rate of Gram-negative bacteria accounted for Imipenem was under 20.0％,and the resistance rate of Gram-positive cocci accounted for Linezolid,Mitrofurantoin and Vancomycin were 0.[Conclusions] The main pathogenic bacterium of urinary tract infection was E.coli,the second was E.faecalis.Imipenem has the better susceptivity for Gram-negative bacteria,while Linezolid,Mitrofurantoin and Vancomycin have the better susceptivity for Gram-positive cocci.
