CAJ | 학술논문

2-仲丁胺基-5-(2-氯吡啶-4-基)-1,3,4-噻二唑(BCPT)是早期发现的一个具有良好除草活性的外消旋先导化合物,报道了使用R/S-仲丁胺为原料分别合成BCPT的两个对映异构体的方法.初步生测结果显示,3种噻二唑化合物(外消旋体和两个对映异构体)对稗草的根和茎均表现出较强的抑制作用,其中S-(+)对映异构体对茎的抑制作用强于R-(-)对映异构体和外消旋体,但对根的生长抑制作用三者间没有显著差异.
2-중정알기-5-(2-록필정-4-기)-1,3,4-새이서(BCPT)시조기발현적일개구유량호제초활성적외소선선도화합물,보도료사용R/S-중정알위원료분별합성BCPT적량개대영이구체적방법.초보생측결과현시,3충새이서화합물(외소선체화량개대영이구체)대패초적근화경균표현출교강적억제작용,기중S-(+)대영이구체대경적억제작용강우R-(-)대영이구체화외소선체,단대근적생장억제작용삼자간몰유현저차이.
Both enantiomers of 2-sec-butylamino-5-(2-chloropyrid-4-yl)-1,3,4-thiodiazoles (BCPT),a powerful racemic herbicidal compound which was found in previous research,were synthesized from R-and S-butylamine respectively. The preliminary bioassay results showed that three of the thiodiazoles (racemate and enantiomers) were excellent growth inhibitors to both roots and stems of barnyard grass.The S-( + ) enantiomer was the strongest for stem growth inhibition,and R-(-) enantiomer was the weakest. But they had little inhibiting difference on root growth.