CAJ | 학술논문

研究垂体腺瘤的临床激素过多症状与腺瘤组织激素检测之间的关系以及该病的发生、生物学行为、分类。方法：对180例垂体腺瘤进行了临床病理分析，并对其中110例应用免疫组化ABC法检测了肿瘤的GH、PRL、ACTH、TSH、FSH、LH。结果：临床激素过多症状与激素检测相一致者占40%，且女性较男性相一致者多，差异有显著性。免疫组化分型以PRL和GH腺瘤多见，多激素腺瘤以GH+PRL腺瘤多见。结论：垂体腺瘤的免疫组化检测与形态功能相结合的分类方法简便易行较为实用。
연구수체선류적림상격소과다증상여선류조직격소검측지간적관계이급해병적발생、생물학행위、분류。방법：대180례수체선류진행료림상병리분석，병대기중110례응용면역조화ABC법검측료종류적GH、PRL、ACTH、TSH、FSH、LH。결과：림상격소과다증상여격소검측상일치자점40%，차녀성교남성상일치자다，차이유현저성。면역조화분형이PRL화GH선류다견，다격소선류이GH+PRL선류다견。결론：수체선류적면역조화검측여형태공능상결합적분류방법간편역행교위실용。
To study the histogenesis, biological behaviour, classification of pituitary adenoma and the relationship between the symptoms of hormonal hypersecretion and the hormone test in pituitary adenoma. Methods One hundred and eighty cases of pituitary adenoma were investigated by clinicopatholgic analysis, and GH, PRL, ACTH, TSH, FSH, LH were examined in 110 cases by ABC immunocytochemical methods. Results Forty percent of the patients were found to have the identical results between the clinical symptoms and hormonal test. Female patients were more than male ones, and the difference was satistically significant. The results showed that PRL and GH adenoma were often found in the cases by immunocytochemical method,and mixed GH-PRL adenoma were often found in the cases with multihormono-adenoma. Conclusion The classification is practical and easy to operate, which combines the immunohistochemical examination of pituipary adenoma with the morphology and function.