CAJ | 학술논문

目的:研究舌根隧道法射频治疗中舌根不同部位损伤体积,探讨其治疗的安全性.方法:18个新鲜离体猪舌随机分成6个组,每组3只.参照Powell等介绍方法在猪舌根选取6个射频操作点.用低温等离子射频发生仪进行猪舌根射频操作,取能级6,作用时间10 s.作用后的舌根组织块进行连续冷冻切片,间隔200 μm保留切片1张,苏木精-伊红染色后,进行序列组织切片的全貌二维图像采集,对损伤区域进行图像分割,提取.将提取分割图像导入IPS图像处理软件,进行损伤区域的三维重建及体积计算.结果:各作用点体积分别为(359.5±5.6)mm~3、(364.3±7.0)mm~3、(363.7±7.2)mm~3、(354.1±11.8)mm~3、(349.4±17.2)mm~3、(353.5±7.9)mm~3,舌根各作用点射频损伤体积差异无统计学意义(P＞0.05).结论:在舌根隧道法射频治疗中,相同作用能级和作用时间下不同作用点损伤体积一致.低温等离子射频治疗系统作用能量集中,舌根区域损伤范围局限,在舌根区域操作具有较高的安全性.
목적:연구설근수도법사빈치료중설근불동부위손상체적,탐토기치료적안전성.방법:18개신선리체저설수궤분성6개조,매조3지.삼조Powell등개소방법재저설근선취6개사빈조작점.용저온등리자사빈발생의진행저설근사빈조작,취능급6,작용시간10 s.작용후적설근조직괴진행련속냉동절편,간격200 μm보류절편1장,소목정-이홍염색후,진행서렬조직절편적전모이유도상채집,대손상구역진행도상분할,제취.장제취분할도상도입IPS도상처리연건,진행손상구역적삼유중건급체적계산.결과:각작용점체적분별위(359.5±5.6)mm~3、(364.3±7.0)mm~3、(363.7±7.2)mm~3、(354.1±11.8)mm~3、(349.4±17.2)mm~3、(353.5±7.9)mm~3,설근각작용점사빈손상체적차이무통계학의의(P＞0.05).결론:재설근수도법사빈치료중,상동작용능급화작용시간하불동작용점손상체적일치.저온등리자사빈치료계통작용능량집중,설근구역손상범위국한,재설근구역조작구유교고적안전성.
Objective:To investigate lesion size caused by channel radiofrequency volumetric reduction of por-cine tongue base in vitro using the technique of three-dimensional reconstruction. And to evaluate safety about channel radiofrequency volumetric reduction of tongue base. Method: Eighteen fresh porcine tongues were randomly separated into six groups,and each group had three ones. The tongue bases were designed six points according to description of Powell. Tongues base were acted on 10 s and 6 level by Coblation radiofrequency system and were cut into serial freezing histological sections. These segments were sectioned at 20 μm on the injury lesion and stained with H & E. Collected 2D digital imagine of order histological sections, drawn and cut apart part of the le-sion of these sections. Images were procesed IPS and were taken three-dimensional reconstruction and statistics an-alyzes with SPSS10. 0. Result: The mean value of tongue base lesion volumes among points was (359. 5± 5. 6)mm~3 ,(364. 3±7. 0)mm~3 ,(363. 7±7. 2)mm~3, (354. 1±11. 8)mm~3, (349. 4±17. 2)mm~3 ,(353. 5±7. 9)mm~3 separately. Statistic analysis by one-way ANOVA showed that there was a insignificant difference between the groups(P>0. 05). Conclusion:These results demonstrated no significant effect lesion size in channel radiofrequency volumetric reduction in the different points of the tongue base. These data also indicated that coblation radiofre-quency system is a safe method for obstructive sleep apnea hypopnea syndrome.