上海交通大学学报（医学版）
上海交通大學學報（醫學版）
상해교통대학학보（의학판）
JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY(MEDICAL SCIENCE)
2010年
1期
42-45
,共4页
恶性肿瘤%静息能量消耗%炎症因子
噁性腫瘤%靜息能量消耗%炎癥因子
악성종류%정식능량소모%염증인자
malignant tumor%resting energy expenditure%inflammatory cytokine
能量代谢是指三大营养物质在体内代谢过程中伴随的能量产生和利用过程.肿瘤本身的作用、机体对肿瘤的反应以及抗肿瘤治疗使肿瘤患者的代谢具有特殊性.通常认为,初诊肿瘤患者的静息能量消耗增加,且与C反应蛋白和一些炎症细胞因子的释放相关;经有效治疗后,静息能量消耗则不同程度下降.肿瘤的分期及分化程度对机体代谢也有影响,但不同的研究结果存在矛盾.文章就肿瘤患者的能量代谢特点及相关影响因素进行综述.
能量代謝是指三大營養物質在體內代謝過程中伴隨的能量產生和利用過程.腫瘤本身的作用、機體對腫瘤的反應以及抗腫瘤治療使腫瘤患者的代謝具有特殊性.通常認為,初診腫瘤患者的靜息能量消耗增加,且與C反應蛋白和一些炎癥細胞因子的釋放相關;經有效治療後,靜息能量消耗則不同程度下降.腫瘤的分期及分化程度對機體代謝也有影響,但不同的研究結果存在矛盾.文章就腫瘤患者的能量代謝特點及相關影響因素進行綜述.
능량대사시지삼대영양물질재체내대사과정중반수적능양산생화이용과정.종류본신적작용、궤체대종류적반응이급항종류치료사종류환자적대사구유특수성.통상인위,초진종류환자적정식능량소모증가,차여C반응단백화일사염증세포인자적석방상관;경유효치료후,정식능량소모칙불동정도하강.종류적분기급분화정도대궤체대사야유영향,단불동적연구결과존재모순.문장취종류환자적능량대사특점급상관영향인소진행종술.
Energy metabolism refers to the metabolism of three major nutrients associated with the process of energy production and usage.The metabolism in patients with tumors manifests specifically, as a result of tumor-bearing state, host's response to tumor and anti-neoplastic therapy.It is believed that resting energy expenditure increases in patients with newly diagnosed tumors, which is related to C-reactive protein and release of inflammatory cytokines. After eflfectjve therapy,resting energy expenditure decreases in some degree.In addition,the stage and differentiation of tumors also affect metabolism.However,there are some conflicts among research findings.The characteristics of energy metabolism and influential factors in patients with tumors are reviewed in this paper.
