CAJ | 학술논문

目的探讨急诊重症监护病房(EICU)中B型利钠肽(BNP)对老年非心原性危重症患者28 d病死率的预测价值.方法连续选取EICU老年非心原性危重症患者70例,收集临床资料,检测BNP水平并随访患者28 d内是否死亡.结果 28 d内共有22例(31.4%)患者死亡,死亡组BNP水平的自然对数值明显高于存活组,分别为(6.4±1.2)ng/L与(5.1±1.5)ng/L(P＜0.05),BNP预测EICU老年危重症患者28 d病死率所得出接收者操作特征曲线下面积为0.759(95%可信区间0.636～0.882,P＜0.05),BNP预测EICU老年危重症患者28 d病死率最佳临界点为342 ng/L,敏感度为77.3%,特异度为68.7%,Youden指数为0.460.结论 BNP可作为预测老年非心原性危重症患者28 d病死率方便快捷的预测指标.
목적 탐토급진중증감호병방(EICU)중B형리납태(BNP)대노년비심원성위중증환자28 d병사솔적예측개치.방법 련속선취EICU노년비심원성위중증환자70례,수집림상자료,검측BNP수평병수방환자28 d내시부사망.결과 28 d내공유22례(31.4%)환자사망,사망조BNP수평적자연대수치명현고우존활조,분별위(6.4±1.2)ng/L여(5.1±1.5)ng/L(P＜0.05),BNP예측EICU노년위중증환자28 d병사솔소득출접수자조작특정곡선하면적위0.759(95%가신구간0.636～0.882,P＜0.05),BNP예측EICU노년위중증환자28 d병사솔최가림계점위342 ng/L,민감도위77.3%,특이도위68.7%,Youden지수위0.460.결론 BNP가작위예측노년비심원성위중증환자28 d병사솔방편쾌첩적예측지표.
Objective To explore the prognostic value of B-type natriuretic peptide (BNP) for 28-day mortality of elderly patients with non-cardiac critical ill in emergency intensive care unit (EICU). Methods A total of 70 elderly non-cardiac critically ill patients (age≥60 years) in EICU were enrolled, and the blood samples were collected to detect BNP level after the patients' admission to EICU. After 28 days, the mortality was assessed. Results Twenty-two patients (31.4 %) died during 28 days observation, whose BNP levels were significantly higher than that of the survivors [ln BNP: (6.4 ± 1.2) ng/L vs. ( 5. 1 ± 1.5 ) ng/L, P＜ 0. 05] ; BNP level had an area under the receiver operating characteristic curve of 0. 759 (95% CI: 0. 636-0. 882, P＜0.05) for predicting mortality,and the optimal cut point of BNP was 342 ng/L (sensitivity 77.3%, specificity 68.7%).Conclusions BNP level could be a predictor for 28-days mortality for elderly non-cardiac critically ill patients.