CAJ | 학술논문

目的检测住院原发性高血压伴有糖代谢异常患者的数据,为全面干预危险因素提供科学依据.方法选择既往无糖代谢异常病史,空腹血糖<5.6 mmol/L确诊为原发件高血压的586例住院患者行口服葡萄糖耐量试验(OGYT)后2 h的血糖测定.观察年龄、性别、体质指数、入院时血压、血尿酸、血脂、动脉硬化等参数与OGTT后2 h血糖的关系.结果 (1)586例患者中检出糖耐量减低患者159例(27.1%);2型糖尿病患者41例(7.0%).(2)糖代谢异常的患者动脉硬化的比例高达67.5%,高于血糖正常组的59.6%,年龄标化后比较差异无统计学意义.结论原发性高血压患者合并糖耐量异常的比例高,对于合并代谢综合征的原发性高血压患者,应积极行OGTT测定,以早期发现和干预糖代谢紊乱,减少动脉硬化的发生.
목적 검측주원원발성고혈압반유당대사이상환자적수거,위전면간예위험인소제공과학의거.방법 선택기왕무당대사이상병사,공복혈당<5.6 mmol/L학진위원발건고혈압적586례주원환자행구복포도당내량시험(OGYT)후2 h적혈당측정.관찰년령、성별、체질지수、입원시혈압、혈뇨산、혈지、동맥경화등삼수여OGTT후2 h혈당적관계.결과 (1)586례환자중검출당내량감저환자159례(27.1%);2형당뇨병환자41례(7.0%).(2)당대사이상적환자동맥경화적비례고체67.5%,고우혈당정상조적59.6%,년령표화후비교차이무통계학의의.결론 원발성고혈압환자합병당내량이상적비례고,대우합병대사종합정적원발성고혈압환자,응적겁행OGTT측정,이조기발현화간예당대사문란,감소동맥경화적발생.
Objective To observe the incidence of impaired glucose tolerance in hospitalized patients with essential hypertension without diabetes mellitus history and with normal fasting glucose. Methods A total of 586 hospitalized patients with essential hypertension and without known diabetes mellitns (DM) and with normal fasting blood glucose (FBG < 5.6 mmol/L) were included in this epidemiologlc cross--sectional survey and screening study and received oral glucose tolerance test (OGTT).Associations between postprandial blood sugar and age, gender, body mass index, blood pressure level,blood lipid level, carotid arterial sclerosis were analyzed. Results (1) Among 586 patients, the number of impaired glucose tolerance (IGT) was 159,the number of newly diagnosed DM was 41 and the prevalence rates of newly diagnosed DM and impaired glucose tolerance (IGT) were 7.0% and 27.1% respectively.(2) Incidence of carotid arterial sclerosis was 67.5% in patients with impaired glucose tolerance and 59.6% in patients with normal glucose tolerance (P > 0.05 ). Conclusion Our results showed that incidence of newly diagnosed disturbed glucometabolic status is common among patients with essential hypertension without DM history and normal FBG. OGTT should be used as a routine procedure in these patients for the purpose of early intervention in hypertensive patients with abnormal glucometabolic status.