CAJ | 학술논문

目的：研究炮制对黄柏抗氧化作用的影响。方法：采用体外氧自由基生成系统和羟自由基诱导的小鼠肝匀浆脂质过氧化反应方法，评价炮制对黄柏抗氧化作用的影响。结果：黄柏生品、清炒品、盐炙品和酒炙品水提取物和醇提取物可清除次黄嘌呤-黄嘌呤氧化酶系统产生超氧阴离子 (O２·)和 Fenton 反应生成的羟自由基(·OH)，并能抑制羟自由基诱导的小鼠肝匀浆上清液脂质过氧化作用，它们之间抗氧化作用存在一定的差异性。炒炭品则无抗氧化作用。结论：酒炙炮制品醇提取物抗氧化作用较好。
목적：연구포제대황백항양화작용적영향。방법：채용체외양자유기생성계통화간자유기유도적소서간균장지질과양화반응방법，평개포제대황백항양화작용적영향。결과：황백생품、청초품、염자품화주자품수제취물화순제취물가청제차황표령-황표령양화매계통산생초양음리자 (O２·)화 Fenton 반응생성적간자유기(·OH)，병능억제간자유기유도적소서간균장상청액지질과양화작용，타문지간항양화작용존재일정적차이성。초탄품칙무항양화작용。결론：주자포제품순제취물항양화작용교호。
Objective:To investigate the effects of different processing products of Cortex Phellodendri on scavenging oxygen free radicals and anti-lipidperoxidation. Method:The oxygen free radicals generation system and mouse liver homogenate lipid peroxidation in vitro were used. Result:The aqueous and 80% alcohol extracts of raw,stir-fried,stir-fried with salt,stir-fried with yellow alcohol products of Cortex Phellodendri could scavenge superoxide radical(O2*)generated through hypoxanthine-oxidase system and(*OH)generated through Fenton action,and inhibit lipid peroxidation induced by hydroxyl radical generation system,respectively.But the carbonized product has no effect.There are differences among these processed products.Conclusion:80% alcohol extract of stir-fried with yellow alcohol products of Cortex Phellodendri was more intense.