CAJ | 학술논문

目的: 观察梗阻性黄疸病人术后应用羟乙基淀粉(130/0.4)对血浆清蛋白和免疫功能的影响.方法: 将24例梗阻性黄疸病人随机分为对照组和试验组,每组各12例.试验组病人自术后即开始输注羟乙基淀粉(130/0.4)10 mL/(kg·d),至术后第7天;对照组病人输注同等量等渗盐水.并于术后第1、3、5和7天测定血浆ALB含量,于术后第1和第7天检测免疫指标.结果: 两组病人术后第1和第7天血浆ALB含量比较无显著差异(P>0.05),而术后第3和第5天血浆ALB含量有显著性差异(P<0.05).两组病人免疫指标无显著性差异(P>0.05).结论: 梗阻性黄疸病人术后使用羟乙基淀粉(130/0.4)可减轻ALB含量的下降,而对病人免疫功能则无明显影响.
목적: 관찰경조성황달병인술후응용간을기정분(130/0.4)대혈장청단백화면역공능적영향.방법: 장24례경조성황달병인수궤분위대조조화시험조,매조각12례.시험조병인자술후즉개시수주간을기정분(130/0.4)10 mL/(kg·d),지술후제7천;대조조병인수주동등량등삼염수.병우술후제1、3、5화7천측정혈장ALB함량,우술후제1화제7천검측면역지표.결과: 량조병인술후제1화제7천혈장ALB함량비교무현저차이(P>0.05),이술후제3화제5천혈장ALB함량유현저성차이(P<0.05).량조병인면역지표무현저성차이(P>0.05).결론: 경조성황달병인술후사용간을기정분(130/0.4)가감경ALB함량적하강,이대병인면역공능칙무명현영향.
Objective: To investigate the effects of trentment with hydroxythy starch(130/0.4) on the serum albumin and immunologic function in postoperative patients with obstructive jaundice.Methods: 24 patients with obstructive jaundice were randomly divided into the control group(n=12) and hydroxythy starch(130/0.4) (HS) group(n=12). The serum ALB was detected 1d, 3d, 5d, 7d after the operation,and the immunologic index were detected 1d and 7d after the operation.Results: The ALB content of control group and HS group were not significantly different in the postoperative 1d and 7 d(P>0.05) and had significant differences in the postoperative 3 d, 5 d (P<0.05).All immunologic index had no significant differences in the postoperative 1d, 7d (P>0.05).Conclusion: The ALB content of patients with obstructive jaundice may decrease postoperatively. Treatment with hydroxylthy starch(130/0.4) can alleviate the drop of the ALB content. But it has no effects on immunologic function.