CAJ | 학술논문

分析Wistar和Wistar Hannover大鼠经16天后肢悬吊后,比目鱼肌的全单一肌纤维形态变化与蛋白表达差异.发现随着后肢悬吊,Wistar Hannover大鼠的比目鱼肌发生很大变化.尽管两种大鼠肌纤维长度未发生变化,但全单一肌纤维的横断面积,肌核数量等减少度Wistar Hannover大鼠相对较大.后肢悬吊前后的蛋白质组学解析结果表明,热休克蛋白27(HSP27)在两个种别大鼠的比目鱼肌内表现有差异.
분석Wistar화Wistar Hannover대서경16천후지현조후,비목어기적전단일기섬유형태변화여단백표체차이.발현수착후지현조,Wistar Hannover대서적비목어기발생흔대변화.진관량충대서기섬유장도미발생변화,단전단일기섬유적횡단면적,기핵수량등감소도Wistar Hannover대서상대교대.후지현조전후적단백질조학해석결과표명,열휴극단백27(HSP27)재량개충별대서적비목어기내표현유차이.
Effects of 16 days of hindlimb suspension on the characteristics of single soleus muscle fiber were compared between male Wistar and Wistar Hannover rats.The greater effects of unloading were noted in Wistar Hannover rats.The unloading-related reductions of muscle weight and fiber cross-sectional area versus the pre-suspension levels were greater than Wistar rats.Total number of myonuclei in control situation was greater in Wistar Hannover rats,but the more numbers of myonuclei were decreased following unloading.Responses of myonuclear domain levels were similar.The numbers of both quiescent and mitotic active satellite cells in control situation were greater in Wistar rats.But the magnitude of the unloading-related decrease was identical for Wistar Hannover and Wistar rats.Although the level of heat shock protein 27(HSP27)expression in Wistar rats was decreased by unloading,de novo appearance of HSP27 was noted in Wistar Hannover rats.It is suggested that greater responses of soleus muscle fibers of Wistar Hannover than Wistar rats may be related to the different expression of protein,although the precise mechanism is still unclear.