CAJ | 학술논문

氧自由基在脑梗死的重要危险因素--动脉粥样硬化的形成中起着重要作用,并且是脑梗死后缺血再灌注损伤的主要因素之一.谷胱甘肽过氧化物酶(GPx)是一种重要的抗氧化酶,其主要作用是清除新陈代谢和氧化应激时产生的过多氧自由基.GPx缺乏将会增高脑梗死风险.文章对GPx的生物学特性及与脑梗死的相关性做了综述.
양자유기재뇌경사적중요위험인소--동맥죽양경화적형성중기착중요작용,병차시뇌경사후결혈재관주손상적주요인소지일.곡광감태과양화물매(GPx)시일충중요적항양화매,기주요작용시청제신진대사화양화응격시산생적과다양자유기.GPx결핍장회증고뇌경사풍험.문장대GPx적생물학특성급여뇌경사적상관성주료종술.
Oxygen free radical, an important risk factor for cerebral infarction, plays an important role in the formation of atherosclerosis, and it is one of the major factors of cerebral isehemia-reperfusion injury after cerebral infarction. Glutathione peroxidase (GPx) is a crucial antioxidant enzyme, its main role is to scavenge the excessive oxygen free radicals produced from metabolism or during the oxidative stress. The deficiency of GPx will increase the risk of cerebral infarction. This article reviews the biological characteristics of GPx and its correlation with cerebral infarction.