CAJ | 학술논문

目的研究右美托咪定用于围脑干肿瘤切除术后带管患者对气管导管的耐受性.方法选取围脑干肿瘤患者40例,常规全麻下行围脑干肿瘤切除手术.术毕前30 min随机分为两组:D组右美托咪定0.3～0.5 μg·kg-1·h-1静脉泵注至术后24 h,M组咪达唑仑0.05 mg·kg-1·h-1静脉泵注至术后24h.观察患者对气管导管的耐受性以及血流动力学指标和呼吸指标的变化.结果 D组20例患者均对气管导管的耐受性良好,且血流动力学及呼吸指标稳定.M组患者中5例对气管导管不能耐受,5例耐受性欠佳,10例耐受良好；M组患者有轻度呼吸抑制,血流动力学指标波动明显.结论右美托咪定用于术后带管患者,气管导管耐受性良好、无呼吸抑制、血流动力学稳定,是对术后带管患者理想的解决方案.
목적 연구우미탁미정용우위뇌간종류절제술후대관환자대기관도관적내수성.방법 선취위뇌간종류환자40례,상규전마하행위뇌간종류절제수술.술필전30 min수궤분위량조:D조우미탁미정0.3～0.5 μg·kg-1·h-1정맥빙주지술후24 h,M조미체서륜0.05 mg·kg-1·h-1정맥빙주지술후24h.관찰환자대기관도관적내수성이급혈류동역학지표화호흡지표적변화.결과 D조20례환자균대기관도관적내수성량호,차혈류동역학급호흡지표은정.M조환자중5례대기관도관불능내수,5례내수성흠가,10례내수량호；M조환자유경도호흡억제,혈류동역학지표파동명현.결론 우미탁미정용우술후대관환자,기관도관내수성량호、무호흡억제、혈류동역학은정,시대술후대관환자이상적해결방안.
Objective To investigate the clinical application of dexmedetomidine on the patients with endotracheal tube after brain surgery.Methods 40 patients undergoing elective surgery for excision of brain stem tumor under general anesthesia were enrolled and randomly divided into 2 groups,dexmedetomidine group (group D,n=20) and midazolam group (group M,n=20).Dexmedetomidine 0.3-0.5 μ g·kg-1 ·h-1was administered for 24 hours to the patients in group D,while midazolam 0.05 mg·kg-1·h-1 was administered for 24 hours to the patients in group M.The tolerance to the endotracheal tube,the parameters of hemodynamics and respiration were recorded.Results All patients in group D tolerated to the endotracheal tube very well.The hemodynamic parameters and the parameters of respirstion in group D were stable.In group M,5 patients could not tolerate to the endotracheal tube,5 patients tolerated to the endotracheal tube not very well and 10 ones did well.Mild respiratory depression was recorded in group M,and the parameters of hemodynamics in group M fluctuated obviously.Conclusion The patients with endotracheal tube after surgery administered with dexmedetomidine tolerate to the endotracheal tube very well,the hemodynamic and respiratory parameters are stable.