CAJ | 학술논문

[目的]确定超声波法提取丹参(Salvia miltiorrhiza Bunge)中丹参酮IIA的最佳提取工艺条件.[方法]以丹参药材为原料,在单因子试验基础上,采用正交试验对丹参酮IIA的超声波辅助提取工艺进行了优化,并用HPLC法测定了提取物中丹参酮IIA的含量.[结果]优化的提取条件为:在室温下,提取剂乙醇体积分数85%,提取时间30 min,料液比(M∶ V)1∶ 10,提取次数4次.在优化提取条件下,提取液中丹参酮IIA的含量可达到0.388%.[结论]用超声波法提取丹参酮IIA快速、高效、方便、节能,有利于规模化生产.
[목적]학정초성파법제취단삼(Salvia miltiorrhiza Bunge)중단삼동IIA적최가제취공예조건.[방법]이단삼약재위원료,재단인자시험기출상,채용정교시험대단삼동IIA적초성파보조제취공예진행료우화,병용HPLC법측정료제취물중단삼동IIA적함량.[결과]우화적제취조건위:재실온하,제취제을순체적분수85%,제취시간30 min,료액비(M∶ V)1∶ 10,제취차수4차.재우화제취조건하,제취액중단삼동IIA적함량가체도0.388%.[결론]용초성파법제취단삼동IIA쾌속、고효、방편、절능,유리우규모화생산.
[Objective]The aim was to optimize the extraction condition of tanshinone IIA from Salvia miltiorrhiza Buhge with ultrasonic extraction method. [Method]On the basis of single factor experiment, an optimum extracting technology of tanshinone IIA from S. Miltiorrhiza was investigated through the orthogonal experiment under the ultrasonic wave assistance conditions, then the content of tanshinone IIA in extract was analyzed with HPLC method. [Result]The optimum extraction conditions were as follows: at room temperature, ethanol volume fraction 85%, extraction time 30 min, solid-liquid ratio 1∶ 10, extrating times 4. Under the above conditions, the content of tanshinone IIA in extract was 0.388%. [Conclusion]Extracting tanshinoneIIA with ultrasonic extraction method has characteristics of rapid, efficient, convenient and low energy consumption. It is benefit for producing tanshinoneIIA in large scale.