CAJ | 학술논문

双歧杆菌属是一类厌氧、不活动、无芽胞,定植于人和动物肠道的原籍菌群,研究表明它具有抑制肿瘤细胞增殖,诱导肿瘤细胞凋亡,刺激机体免疫细胞分泌细胞因子,以及作为肿瘤基因治疗靶向载体等特点.体内研究表明,双歧杆菌对机体无毒无害,因此可以作为一种理想生物制剂治疗肿瘤.
쌍기간균속시일류염양、불활동、무아포,정식우인화동물장도적원적균군,연구표명타구유억제종류세포증식,유도종류세포조망,자격궤체면역세포분비세포인자,이급작위종류기인치료파향재체등특점.체내연구표명,쌍기간균대궤체무독무해,인차가이작위일충이상생물제제치료종류.
Bifidohacterium is an inherent intestinal microflora. It is anaerobic, nonpathogenic and bad-less. Researches have demonstrated that bifidohacterium can inhibit tumor cells growth, induce tumor cells apop-tosis and stimulate the immunocytes secreting cytokines. Because it can selectively localizes and proliferates in solid tumors,it can be used as a delivery system for tumor-targeting enzyme-prodrug in geoe therapy. In vivo studies show that bifidobacterium is an ideal biologic agent which can be used to treat tumor without toxicity.