国际医学寄生虫病杂志
國際醫學寄生蟲病雜誌
국제의학기생충병잡지
INTERNATIONAL JOURNAL OF MEDICAL PARASITIC DISEASES
2012年
1期
50-55
,共6页
马红丹%姜玉新%唐小牛%李朝品
馬紅丹%薑玉新%唐小牛%李朝品
마홍단%강옥신%당소우%리조품
变应原疫苗%植物生物反应器%转基因植物
變應原疫苗%植物生物反應器%轉基因植物
변응원역묘%식물생물반응기%전기인식물
Allergen vaccine%Plant bioreactor%Transgenic plants
随着工业化进程的加快,变应性疾病已成为威胁人类健康的严重问题,应用特异性变应原进行脱敏治疗是其惟一有效的办法.新型变应原疫苗的生产研究已成为现今的热门课题之一.近年来随着分子生物学技术的发展,利用转基因植物作为生物反应器生产具有重要经济价值的异源蛋白(特别是医用蛋白)正在成为研究最活跃、产业发展最迅速的热点,该文着重就植物生物反应器近年的发展及其在变应原生产中的应用、优缺点等做一简单综述.
隨著工業化進程的加快,變應性疾病已成為威脅人類健康的嚴重問題,應用特異性變應原進行脫敏治療是其惟一有效的辦法.新型變應原疫苗的生產研究已成為現今的熱門課題之一.近年來隨著分子生物學技術的髮展,利用轉基因植物作為生物反應器生產具有重要經濟價值的異源蛋白(特彆是醫用蛋白)正在成為研究最活躍、產業髮展最迅速的熱點,該文著重就植物生物反應器近年的髮展及其在變應原生產中的應用、優缺點等做一簡單綜述.
수착공업화진정적가쾌,변응성질병이성위위협인류건강적엄중문제,응용특이성변응원진행탈민치료시기유일유효적판법.신형변응원역묘적생산연구이성위현금적열문과제지일.근년래수착분자생물학기술적발전,이용전기인식물작위생물반응기생산구유중요경제개치적이원단백(특별시의용단백)정재성위연구최활약、산업발전최신속적열점,해문착중취식물생물반응기근년적발전급기재변응원생산중적응용、우결점등주일간단종술.
Along with industrialization process,allergic disease has been a serious problem to human health.It is the unique effective way that the desensitization treatment is performed with specific allergens.Up to date,it is also a hot spot that novel allergen vaccines are produced.Following the development of molecular biology,it is one of the most active and best fields that foreign proteins with important economical value ( especially proteins using as medicine),are produced in transgenic plants as bioreactors.This paper reviewed the development of plant bioreactors,their applications in allergen production,and their advantages and disadvantages.