CAJ | 학술논문

目的评价中西医结合治疗恶性胸腔积液的临床疗效.方法回顾性分析2009年10月至2012年3月我院90例恶性胸腔积液患者,随机分为两组各45例,对照组应用胸腔灌注化疗药物治疗,治疗组给予中西医结合治疗,观察并比较两组临床疗效、毒副反应及患者的生活质量情况.结果治疗组总有效率为86.7％,对照组为62.2％,两组总有效率比较差异具有显著性(P＜0.05).治疗组患者生活质量改善明显优于对照组(P＜0.05).治疗后主要不良反应为恶心呕吐、胸痛、发热.治疗组不良反应发生率为8.9％,明显低于对照组的26.7％(P＜ 0.05).结论中西医结合治疗恶性胸腔积液能显著提高近期疗效,改善生活质量,值得临床推广.
목적 평개중서의결합치료악성흉강적액적림상료효.방법 회고성분석2009년10월지2012년3월아원90례악성흉강적액환자,수궤분위량조각45례,대조조응용흉강관주화료약물치료,치료조급여중서의결합치료,관찰병비교량조림상료효、독부반응급환자적생활질량정황.결과 치료조총유효솔위86.7％,대조조위62.2％,량조총유효솔비교차이구유현저성(P＜0.05).치료조환자생활질량개선명현우우대조조(P＜0.05).치료후주요불량반응위악심구토、흉통、발열.치료조불량반응발생솔위8.9％,명현저우대조조적26.7％(P＜ 0.05).결론 중서의결합치료악성흉강적액능현저제고근기료효,개선생활질량,치득림상추엄.
Objective To evaluate the efficacy of combining traditional Chinese and western medicine for treatment of malignant pleural effusion.Methods Retrospective analysis of 90 patients with malignant pleural effusion from October 2009 to March 2012,which were randomly divided into two groups,control group received intrapleural perfusion chemotherapy,treatment group received combining traditional Chinese and western medicine.Clinical efficacy and incidence of adverse reaction were compared between them.Results The total effective ratio in treatment group was 86.7％.The control group was 62.2％.There were significant differences in total effective ratio between two groups(P＜ 0.05).Improvement of life quality in treatment group was better than that in control group(P＜ 0.05).The main adverse reactions were nausea and vomiting,chest pain and fever.The incidence of adverse reactions in treatment group was 8.9％, significantly lower than that (26.7％) of the control group (P ＜ 0.05).Conclusion Combining traditional Chinese and western medicine can improve short-term clinical effect and quality of life of patients with malignant pleural effusion,which should be worthy of clinical application.