CAJ | 학술논문

目的探讨前颅底肿瘤的手术入路及颅底重建的价值.方法回顾性分析浙江省肿瘤医院神经外科自1994年9月至2008年6月行手术切除并行颅底重建的47例前颅底肿瘤患者的临床资料,其中采用前颅底入路7例,扩大前颅底入路8例.颅面联合入路32例,且采用颅骨膜瓣、颅骨膜额肌瓣为主的颅底修复技术.结果本组肿瘤全切率为70.3%(33/47),大部分切除率为25.5%(12/47),部分切除率为4.2%(2/47);并发症发生率为21.2%(10/47).结论三种入路能完成各型前颅底肿瘤切除;运用骨膜瓣、颅骨膜额肌瓣为主的颅底修复技术安全有效,并发症少,对术后放疗有很好的放疗耐受性.
목적 탐토전로저종류적수술입로급로저중건적개치.방법 회고성분석절강성종류의원신경외과자1994년9월지2008년6월행수술절제병행로저중건적47례전로저종류환자적림상자료,기중채용전로저입로7례,확대전로저입로8례.로면연합입로32례,차채용로골막판、로골막액기판위주적로저수복기술.결과 본조종류전절솔위70.3%(33/47),대부분절제솔위25.5%(12/47),부분절제솔위4.2%(2/47);병발증발생솔위21.2%(10/47).결론 삼충입로능완성각형전로저종류절제;운용골막판、로골막액기판위주적로저수복기술안전유효,병발증소,대술후방료유흔호적방료내수성.
Objective To demonstrate various operative approaches to the removal of the tumors involving the anterior skull base and explore the effectiveness of the pericraniai flap in reconstructing the anterior skull base. Methods The clinical data of 47 patients with anterior skull-based tumors were retrospectively reviewed and analyzed: subffontal approach, extended subfrontal approach and combined craniofacial approaches were performed in 7, 8 and 32 patients, respectively; pericranial flap and galeo-pericranial flap were employed in the reconstructing the anterior skull base. Results Tumors were radically resected in 33, subtotally resected in 12 and partly resected in 2 patients with 21.2% overall complication rate. Conclusion The 3 approaches are highly effective in the removal of anterior skull-based tumors. The pericranial flap or galeo-pericranial flap was reliably and effectively used in the reconstructing anterior skull base with minimally complication rate and excellent endurance of postoperative radiotherapy.