CAJ | 학술논문

目的探讨熊去氧胆酸治疗慢性乙型肝炎患者持续性γ-谷氨酰转肽酶(GGT)升高的疗效.方法 69例患者随机分为治疗组(35例)和对照组(34例),治疗组予以常规保肝治疗和熊去氧胆酸(UDCA)口服,对照组单独予以常规保肝治疗.分别检测两组治疗15 d和30 d时GGT的水平.结果对照组和治疗组在治疗15 d和30 d时GGT值比较差异均有统计学意义(P＜0.05).结论熊去氧胆酸能快速、有效地降低慢性乙型肝炎患者持续升高的GGT.
목적 탐토웅거양담산치료만성을형간염환자지속성γ-곡안선전태매(GGT)승고적료효.방법 69례환자수궤분위치료조(35례)화대조조(34례),치료조여이상규보간치료화웅거양담산(UDCA)구복,대조조단독여이상규보간치료.분별검측량조치료15 d화30 d시GGT적수평.결과 대조조화치료조재치료15 d화30 d시GGT치비교차이균유통계학의의(P＜0.05).결론 웅거양담산능쾌속、유효지강저만성을형간염환자지속승고적GGT.
Objective To investigate the effects of ursodeoxycholic acid on lowering continuously elevated gamma glutamyl transpeptidase(GGT) levels in patients suffering from chronic hepatitis B virus.Methods Patients in the treatment group were given conventional liver protecting treatment in combination with oral ursodeoxycholic acid therapy, in a dose of 250 mg twice a day.And patients in control group were given conventional liver protecting treatment.The GGT levels were detected on the 15th day and 30th day after treatment.Results There were significant differences of GGT levels between the treatment group and control group on the 15th day and 30th day affer therapy (P<0.05).Conclusions Ursodeoxycholic acid can lower the continuously elevated GGT levels in patients with chronic hepatitis B virus quickly and effectively.