医学信息(内·外科版)
醫學信息(內·外科版)
의학신식(내·외과판)
MEDICAL INFORMATION SECTION OF OPERATIVE SURGERY
2009年
6期
510-511
,共2页
先天性唇腭裂%危险因素
先天性脣腭裂%危險因素
선천성진악렬%위험인소
cleft lip and cleft palate%risk factors
目的 探讨先天性唇腭裂的危险因素,为预防先天性唇腭裂患儿出生提供科学的依据.方法 对先天性唇腭裂患儿285例行1:1病例对照研究.结果 家族史情况、孕早期放射线照射情况、毒物接触情况、孕早期感染情况以及孕妇的精神、职业6个因素与唇腭裂的发生有统计学联系(P<0.05).结论 预防先天性唇腭裂患儿的出生,必须作好产前诊断,避免接触环境中的致畸因素,保持孕期身体健康和精神愉快.
目的 探討先天性脣腭裂的危險因素,為預防先天性脣腭裂患兒齣生提供科學的依據.方法 對先天性脣腭裂患兒285例行1:1病例對照研究.結果 傢族史情況、孕早期放射線照射情況、毒物接觸情況、孕早期感染情況以及孕婦的精神、職業6箇因素與脣腭裂的髮生有統計學聯繫(P<0.05).結論 預防先天性脣腭裂患兒的齣生,必鬚作好產前診斷,避免接觸環境中的緻畸因素,保持孕期身體健康和精神愉快.
목적 탐토선천성진악렬적위험인소,위예방선천성진악렬환인출생제공과학적의거.방법 대선천성진악렬환인285례행1:1병례대조연구.결과 가족사정황、잉조기방사선조사정황、독물접촉정황、잉조기감염정황이급잉부적정신、직업6개인소여진악렬적발생유통계학련계(P<0.05).결론 예방선천성진악렬환인적출생,필수작호산전진단,피면접촉배경중적치기인소,보지잉기신체건강화정신유쾌.
Objective To find the methods how to prevent the birth of infants through analyzing the risk factor of congenital cleft lip and cleft palate. Methods A case control study was conducted among the parents of 285 infants with cleft lip and cleft palate and the parents of 285 normal infants who were matched as the control. Results Accord-ing to simple factor analysis,6 factors were significantly associated with cleft lip and cleft palate(P <0. 05) ,including family history of cleft lip and cleft palate,ray irradiation,the toxic exposure,early infection,mental stress and job occu-pation in duration of pregnancy. Conclusions Prevention of congenital cleft lip and palate at birth, prenatal diagnosis must be ready to avoid exposure to teratogenic factors in the environment, and maintain good health during pregnancy and mental pleasure.