CAJ | 학술논문

肿瘤细胞的葡萄糖代谢主要呈现出瓦博格效应(Warburg effect).近年来,越来越多的实验证实基于肿瘤细胞有氧糖酵解途径的治疗可通过抑制多种分子、基因和信号途径限制能量供应,抑制肿瘤细胞增殖.这为肿瘤的靶向治疗提供了契机,具有巨大的潜在优势和广阔的临床应用前景.
종류세포적포도당대사주요정현출와박격효응(Warburg effect).근년래,월래월다적실험증실기우종류세포유양당효해도경적치료가통과억제다충분자、기인화신호도경한제능량공응,억제종류세포증식.저위종류적파향치료제공료계궤,구유거대적잠재우세화엄활적림상응용전경.
Glucose metabolism of cancer cells presents Warburg effect.In resent years,more and more experiments demonstrate that the therapeutics based on aerobic glycolysis pathway in cancer cells restrict energy and inhibit tumor proliferation through the inhibition of a variety of moleculars,genes and signal pathways.These can provide an opportunity for targeted cancer therapies and possess enormous potential advantages and broad prospects in clinical application.