CAJ | 학술논문

miR-205在多种肿瘤中存在差异性表达,与肿瘤的发生发展及转移等过程密切相关.miR-205可通过与特定靶基因结合参与调控肿瘤细胞的增殖、分化、原位侵袭及远处转移等生物学行为.对miR-205的深入研究,有望对肿瘤的诊断、靶向治疗及预后等发挥重要作用.
miR-205재다충종류중존재차이성표체,여종류적발생발전급전이등과정밀절상관.miR-205가통과여특정파기인결합삼여조공종류세포적증식、분화、원위침습급원처전이등생물학행위.대miR-205적심입연구,유망대종류적진단、파향치료급예후등발휘중요작용.
miR-205 is differentially expressed in tumor tissues and is closely related to tumorigenesis and tumor metastasis.miR-205 can regulate the biological behaviors of tumor cells such as cell proliferation,differentiation,in situ invasion and distant metastasis by post-transcriptional regulation through binding to targeted genes.Additionally,further research of miR-205 may be helpful for tumor diagnosis,targeted therapy and prognosis.