CAJ | 학술논문

目的比较角膜缘干细胞移植和羊膜移植对复发性翼状胬肉的疗效.方法将81例(94只眼)复发性翼状胬肉患者随机分成A、B组;A组45例(48只眼)行翼状胬肉切除联合自体角膜缘干细胞移植术；B组36例(46只眼)行翼状胬肉切除术联合羊膜移植术.随诊1.5年,观察两组患者的角膜修复时间、复发率及并发症.结果 A组3例患者(3只眼)翼状胬肉复发,复发率为6.3％；B组7例患者(10只眼)翼状胬肉复发,复发率为21.7％,两组比较,差异有统计学意义(x2=4.729,P=0.03).结论角膜缘干细胞移植术与羊膜移植术相比能明显的降低复发率,减少角膜修复时间,是治疗复发性翼状胬肉的好方法.
목적 비교각막연간세포이식화양막이식대복발성익상노육적료효.방법 장81례(94지안)복발성익상노육환자수궤분성A、B조;A조45례(48지안)행익상노육절제연합자체각막연간세포이식술；B조36례(46지안)행익상노육절제술연합양막이식술.수진1.5년,관찰량조환자적각막수복시간、복발솔급병발증.결과 A조3례환자(3지안)익상노육복발,복발솔위6.3％；B조7례환자(10지안)익상노육복발,복발솔위21.7％,량조비교,차이유통계학의의(x2=4.729,P=0.03).결론 각막연간세포이식술여양막이식술상비능명현적강저복발솔,감소각막수복시간,시치료복발성익상노육적호방법.
Objective To evaluate the therapeutic effects of limbal epithelial autograft and amniotic membrane grafting on recurrent pterygium. Methods There were 81 patients (94 eyes) with first recurrent pterygium and they were allocated two groups:excision of pteryginm with limbal epithelial autograft transplantation surgery (group A,45 cases with 48 eyes) and excision of pterygium with amniotic membrane grafting (group B,36 cases with 46 eyes),the post-operative follow-up periods ranged 18 months to analyze the recurrent rate,the repair time of epithelium and complication.Results In the eyes follow-up 3 of 48 eyes (6.3％) in group A and 10 of 46 eyes (21.7％) in group B were recurred.There was difference in recurrent rate between the two groups (x2=4.729,P =0.03).Conclusions Limbal epithelial autograt transplantation can reduce the recurrence and make the repair time of epithelium lower,It is a reasonable therapeutic method for the treatment of recurrent prerygium than amniotic membrane grafting.