中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
9期
993-995
,共3页
左炔诺孕酮宫内缓释系统%功能失调性子宫出血%子宫内膜
左炔諾孕酮宮內緩釋繫統%功能失調性子宮齣血%子宮內膜
좌결낙잉동궁내완석계통%공능실조성자궁출혈%자궁내막
Levonorgestrel-releasing intrauterine device%Dysfunctional uterine bleeding%Endometrial hyperplasia
目的 观察左炔诺孕酮宫内缓释系统(LNG-IUS;商品名:曼月乐)对功能失调性子宫出血的临床疗效。方法 对45例子宫内膜诊刮病理诊断为功能失调性子宫出血患者放置左炔诺孕酮宫内缓释系统,在放置前和放置满24个月内定期B超监测子宫内膜厚度,观察患者血红蛋白情况及月经改善情况。结果 置LNG-IUS前子宫内膜厚度为(15.6±4.2)mm,置LNG-IUS 24个月子宫内膜厚度为(3.2±1.3)mm,两者比较差异有统计学意义(U=2.82,P＜0.01);放置LNG-IUS 6个月后患者血红蛋白显着升高[(97.6±8.2)g/L升到(123.7±8.1) g/L],差异有统计学意义(U=2.26,P＜0.05)。置LNG-IUS后患者出现不规则少量子宫出血或点滴出血。结论 左炔诺孕酮宫内缓释系统不但能从临床方面有效地控制月经,对功血有持续的疗效,对复杂型增生的子宫内膜也有抑制作用。
目的 觀察左炔諾孕酮宮內緩釋繫統(LNG-IUS;商品名:曼月樂)對功能失調性子宮齣血的臨床療效。方法 對45例子宮內膜診颳病理診斷為功能失調性子宮齣血患者放置左炔諾孕酮宮內緩釋繫統,在放置前和放置滿24箇月內定期B超鑑測子宮內膜厚度,觀察患者血紅蛋白情況及月經改善情況。結果 置LNG-IUS前子宮內膜厚度為(15.6±4.2)mm,置LNG-IUS 24箇月子宮內膜厚度為(3.2±1.3)mm,兩者比較差異有統計學意義(U=2.82,P＜0.01);放置LNG-IUS 6箇月後患者血紅蛋白顯著升高[(97.6±8.2)g/L升到(123.7±8.1) g/L],差異有統計學意義(U=2.26,P＜0.05)。置LNG-IUS後患者齣現不規則少量子宮齣血或點滴齣血。結論 左炔諾孕酮宮內緩釋繫統不但能從臨床方麵有效地控製月經,對功血有持續的療效,對複雜型增生的子宮內膜也有抑製作用。
목적 관찰좌결낙잉동궁내완석계통(LNG-IUS;상품명:만월악)대공능실조성자궁출혈적림상료효。방법 대45례자궁내막진괄병리진단위공능실조성자궁출혈환자방치좌결낙잉동궁내완석계통,재방치전화방치만24개월내정기B초감측자궁내막후도,관찰환자혈홍단백정황급월경개선정황。결과 치LNG-IUS전자궁내막후도위(15.6±4.2)mm,치LNG-IUS 24개월자궁내막후도위(3.2±1.3)mm,량자비교차이유통계학의의(U=2.82,P＜0.01);방치LNG-IUS 6개월후환자혈홍단백현착승고[(97.6±8.2)g/L승도(123.7±8.1) g/L],차이유통계학의의(U=2.26,P＜0.05)。치LNG-IUS후환자출현불규칙소양자궁출혈혹점적출혈。결론 좌결낙잉동궁내완석계통불단능종림상방면유효지공제월경,대공혈유지속적료효,대복잡형증생적자궁내막야유억제작용。
Objective To evaluate the efficacy and side-effects of the levonorgestrel-releasing intrauterine device (Mirena) in the treatment of dysfunctional uterine bleeding .Methods 45 cases of dysfunctional uterine bleeding diagnosed by pathology were installed with Mirena.The endometrial thickness by ultrasound hemoglobulin increase and pathologic changes of endometria were recorded before and 24 months after the installation.Results The endometrial thickness before and after the insertion of Mirena were(15.6 ±4.2) mm and (3.2 ± 1.3) mmrespectively (P ＜ 0.01) .Six months after the insertion of Mirena, patients' hemoglobulin was significantly increased from (97.6 ± 8.2) g/L to (123.7 ± 8.1) g/L (U = 2.26, P ＜ 0.05) .After the installation of Mirena, patient experienced metrorrhagia.Conclusions Mirena is a device providing effective and continual therapy for dysfunctional uterine bleeding .It can not only significantly reduce the menstrual blood loss but also reverse the complex hyperplasia effectively.
