CAJ | 학술논문

基质金属蛋白酶-9(MMP-9)是结直肠癌发生发展的重要促进基因,能够诱导结直肠癌细胞增殖、血管新生和肿瘤浸润,导致结直肠癌的侵袭转移.MMP-9对结直肠癌侵袭转移的影响既可独自完成又可与其他基因联合完成,是结直肠癌晚期转移的重要蛋白酶.
기질금속단백매-9(MMP-9)시결직장암발생발전적중요촉진기인,능구유도결직장암세포증식、혈관신생화종류침윤,도치결직장암적침습전이.MMP-9대결직장암침습전이적영향기가독자완성우가여기타기인연합완성,시결직장암만기전이적중요단백매.
Matrix metalloproteinases-9(MMP-9) is an important gene in coloreetal cancer occurrence and development.MMP-9 can induce cell proliferation,angiogenesis and neoplasm infiltration,and then leads to coloreetal cancer invasion and metastasis.MMP-9 can not only play the role individually in coloreetal canccr invasion and migration,but also can cooperate with other genes.MMP-9 is a key protease in terminal metastasis of coloreetal cancer.